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Easy-Prime applies a machine learning model (i.e., XGboost) that learns important PE design features from multiple published PE data sources to help researchers selecting the best candidate.

Easy-Prime applies a machine learning model (i.e., XGboost) that learned important PE design features from public PE amplicon sequencing data to help researchers selecting the best candidate.

Easy-Prime provides optimized pegRNA and ngRNA combinations for efficient PE design. Visit: http://easy-prime.cc/ PE design involves carefully choosing a standard sgRNA, a RT template that contains the desired edits, a PBS that primes the RT reaction, and a …

Prime editing is a revolutionary genome-editing technology that can make a wide range of precise edits in DNA. However, designing highly efficient prime editors (PEs) remains challenging. We develop Easy-Prime, a machine learning–based program …

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Aug 19, 2021 · Prime editing is a revolutionary genome-editing technology that can make a wide range of precise edits in DNA. However, designing highly efficient prime editors (PEs) remains challenging. We develop Easy-Prime, a machine learning-based program trained with multiple published data sources.

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