A novel Ig superfamily protein, EWI-2, was co-purified with tetraspanin protein CD81 under relatively stringent Brij 96 detergent conditions and identified by mass spectrometric protein …

Feb 14, 2023 · EWI2, also called PGRL, IgSF8, and CD316, is a type I transmembrane protein and belongs to the subfamily of IgSF with all four members encompassing the conserved Glu …

Feb 6, 2015 · Here we demonstrate that changes in the expression level of EWI motif-containing protein 2 (EWI-2, or IgSF8/CD316), a cell surface transmembrane protein, play a key role in …

These results provide new insights into regulation of TGF-β signaling in melanoma, uncover new roles for tetraspanins CD9 and CD81, and strongly suggest that EWI-2 could serve as a …

Jul 15, 2012 · EWI motif-containing protein 2 (EWI-2) is a member of the Ig superfamily that links tetraspanin-enriched microdomains to the actin cytoskeleton. We found that EWI-2 colocalizes …

Apr 23, 2024 · IGSF8 (also known as EWI-2, CD316, LIR-D1) is a member of the EWI subfamily of the immunoglobulin superfamily and has been reported to associate with the tetraspanins …

Nov 2, 2001 · A novel Ig superfamily protein, EWI-2, was co-purified with tetraspanin protein CD81 under relatively stringent Brij 96 detergent conditions and identified by mass …

Jul 14, 2006 · EWI-2 and EWI-F, two members of a novel subfamily of Ig proteins, are direct partners of tetraspanins CD9 (Tspan29) and CD81 (Tspan28). These EWI proteins contain a …

Cell surface transmembrane protein IGFS8 (herein called EWI-2) negatively regulates melanoma TGF-β signaling and is well positioned to control the transition in TGF-β signaling from …

Nov 2, 2001 · A novel Ig superfamily protein, EWI-2, was co-purified with tetraspanin protein CD81 under relatively stringent Brij 96 detergent conditions and identified by mass …