Nov 30, 2016 · T1 maps show diffuse rise in native-T1 values (a1). On LGE-imaging, there is low contrast-noise ratio (CNR) between the blood pool and the myocardium (a2). ECV-maps demonstrate diffuse rise in extra-cellular space in the whole myocardium.

Myocardial native T1 and extracellular volume fraction (ECV) mapping have emerged as cardiac magnetic resonance biomarkers providing unique insight into cardiac pathophysiology. Single breath-hold acquisition techniques, available on clinical scanners across multiple vendor platforms, have made clinical T1 and ECV mapping a reality.

T1 measurements or mapping has been used to quantify ECV by combining native and contrast-enhanced T1 maps of blood and myocardium (Central Illustration). The change of the T1 relaxation rate (i.e., 1/T1) in blood between pre- and post-contrast imaging is converted with the blood hematocrit into a reference for plasma T1, which serves as ...

Oct 9, 2017 · Parametric mapping with CMR now permits the routine spatial visualization and quantification of changes in myocardial composition based on changes in T1, T2, and T2*(star) relaxation times and extracellular volume (ECV).

Fast and easy 3 step workflow to calculate Extracellular Volume (ECV) maps; Flexible automatic breathing motion correction method, applicable for one or multiple T1 series; Easy quantification of delta maps for comparison of the maps; Created maps can be exported as DICOM to add to the patient data ; Choose the color overlay to your own taste

T1 and T2 image mapping sequences enable the direct quantification of T1, T2, and extracellular volume fraction (ECV) values of the myocardium, leading to the progressive integration of these sequences into routine CMR settings.

T1 mapping and extracellular volume (ECV) mapping are steadily becoming diagnostic and prognostically useful tests for in vivo myocardial histology, influencing clinical decision-making.

Jun 7, 2024 · Extracellular volume (ECV) reflects the volume fraction that is not taken by cells. It combines interstitial and intravascular space and represents approximately 25% of the myocardial volume 6.

ECV measurement circumvents factors that confound T1-weighted images or T1-maps, and has been shown to correlate well with diffuse myocardial fibrosis. The goal of this study was to develop and evaluate an automated method for producing a pixel-wise map of ECV that would be adequately robust for clinical work flow.

Apr 18, 2020 · ECV maps derived by acquiring hematocrit (HCT) , native T1, and postcontrast T1 modified Look-Locker inversion recovery of the short axis of a healthy volunteer.