
E-4031 - Wikipedia
E-4031 is an experimental class III antiarrhythmic drug that blocks potassium channels of the hERG-type. [1] E-4031 is a synthesized toxin that is a methanesulfonanilide class III antiarrhythmic drug. [2]
E-4031 dihydrochloride | Voltage-gated Potassium Channels
E-4031 dihydrochloride is a selective blocker of K V 11.1 (hERG) channels; inhibits the rapid delayed-rectifier K + current (I Kr). Reversibly prolongs action potential duration in guinea pig papillary muscle and isolated ventricular myocytes, without affecting Na + …
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E-4031 | C21H27N3O3S | CID 3185 - PubChem
E-4031 | C21H27N3O3S | CID 3185 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
E-4031 | hERG Channels Blocker - MedChemExpress
E-4031 is a selective hERG potassium channel blocker for use in class III anti-arrhythmic studies. - Mechanism of Action & Protocol.
E-4031
E-4031, A potent and selective inhibitor of the rapid type of inactivating inward-rectifying K + current (IK, IR) (IC₅₀ = 10 nM).
E-4031 dihydrochloride | C21H29Cl2N3O3S | CID 3087190
E-4031 dihydrochloride | C21H29Cl2N3O3S | CID 3087190 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
E-4031 =98 HPLC,solid 113559-13-0 - MilliporeSigma
E-4031 is a antiarrhythmic drug and belongs to the class III type. It is a methanesulfonanilide compound and is effective in treating arrhythmia and modulates ventricular fibrillation. E-4031 mediates the prolongation of action potential duration …
E-4031 (hydrochloride) (CAS 113559-13-0) - Cayman Chem
E-4031 (hydrochloride): An antiarrhythmic, ERG potassium channel blocker. CAS Number: 113559-13-0. Purity: ≥98%.
E-4031 | #E-500 | CAS 113559-13-0 | Alomone Labs
High purity E-4031 (#E-500) (CAS 113559-13-0) is a Kv11.1 (hERG) channel blocker from Alomone Labs. A synthetic and biologically active compound. New lots are biologically tested.
Electrophysiologic effects of E-4031, a new class III antiarrhythmic ...
Jun 15, 1993 · Restoration of normal AV conduction by radiofre- quency ablation of accessory pathways enhances atrial transport function as measured by Doppler indexes of LV filling. Consequently, there is an apparent increase in stroke volume as measured by mitral inflow velocity time integrals.