May 10, 2018 · We assessed mitochondrial membrane potential through staining with JC1 where the ratio of red (JC1 aggregate): green (JC1 monomer) depicts mitochondrial viability.

Herein, we provide a practical user guide for monitoring mitochondrial membrane potential in whole cells using a fluorescent cationic probe.

JC-1 staining of breast cancer cells after DOX, PD, and DOX + PD treatments. MCF-7 and MDA-MB-231 cells were treated with 5 μM DOX, 10 μM PD, or 5 μM DOX + 10 μM PD. After 4 h of...

May 17, 2014 · JC1 and H2AX immunofluorescence were used to assess mitochondrial and nuclear DNA damage, respectively. This study demonstrated that AG has a dose-dependent …

JC-1 mitochondrial membrane potential assay is a fluorescence-based method to track the behavior of mitochondria. Mitochondrial membrane potential (MMP) is an important parameter …

JC-1, a cationic fluorescent dye when added to living cells, is known to be localized exclusively in mitochondria, particularly in good physiological conditions characterized by sufficient …

Ratiometric JC-1 imaging reliably unveiled differences in mitochondrial shape, ΔΨ m, and apparently, also the sensitivity to metabolic challenge of individual mitochondria in their cellular …

Mitochondrial membrane potential of the cardiomyocytes was measured by JC-1, an indicator mitochondrial function, in cardiomyocytes treated with Ber (1.0 µM) or/and DOX (1.0 µM) for 1 …

JC-1 (5,5′,6,6′-tetrachloro1,1′,3,3′-tetramethylbenzimidazolylcarbocyanine iodide) dye has been used to monitor mitochondrial potential. The monomeric form has an emission maximum of …

JC-1 has been difficult to dissolve, but this kit solves the problem! HeLa cells treated with depolarizing reagent, carbonylcyanide-p-trifluoromethoxyphenylhydrazone (FCCP) were …