Dideoxynucleotides are chain-elongating inhibitors of DNA polymerase, used in the Sanger method for DNA sequencing. [1] . They are also known as 2',3' because both the 2' and 3' positions on the ribose lack hydroxyl groups, and are abbreviated as ddNTPs (ddGTP, ddATP, ddTTP and ddCTP). [2]

In this study, we describe the details of the 2.3-Å resolution crystal structures of three additional closed ternary complexes of Klentaq1 bound to a primer/template DNA and a ddATP, a ddTTP, or a ddGTP.

In this report, we present the details of the 2.3-A resolution crystal structures of three additional ternary complexes of Klentaq1 bound to a primer/template DNA and a dideoxyguanosine 5'-triphosphate (ddGTP), a dideoxythymidine 5'-triphosphate (ddTTP), or a dideoxyadenosine 5'-triphosphate (ddATP).

ddCTP, or dideoxycytidine triphosphate, is a modified nucleotide used in the DNA sequencing method known as the Sanger sequencing technique. It plays a crucial role in determining the sequence of DNA molecules by acting as a chain terminator during DNA synthesis.

ddCTP is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddCTP is a nucleoside analog that targets the reverse transcriptase of HIV. ddCTP can be used for AIDS research.

2′,3′-Dideoxycytidine 5′-Triphosphate, 100 mM solution (ddCTP). Easy-to-use, time-saving solutions for use in any application requiring ddNTPs of high purity, such as dideoxy sequencing and genotyping reactions. High purity: ? 98% triphosphate.

Jun 24, 1994 · Two ternary complexes of rat DNA polymerase beta (pol beta), a DNA template-primer, and dideoxycytidine triphosphate (ddCTP) have been determined at 2.9 A and 3.6 A resolution, respectively. ddCTP is the triphosphate of dideoxycytidine (ddC), a nucleoside analog that targets the reverse transcriptas …

Molecular Formula: C 9 H 16 N 3 O 12 P 3 (free acid) Molecular Weight: 451.16 g/mol (free acid) Exact Mass: 450.99 g/mol (free acid) CAS#: 66004-77-1. Purity: ≥ 98 % (HPLC) Form: solution in water. Color: colorless to slightly yellow. Concentration: 10 mM - 11 mM. pH: 7.5 ±0.5.

Sep 15, 1997 · Both 2',3'-dideoxycytidine (ddC) and 2',3'-dideoxycytidine 5'-triphosphate (ddCTP) inhibit the synthesis of the major phospholipids phosphatidylcholine (PC) and phosphatidylethanolamine (PE) in permeabilized rat hepatocytes.

2',3'-Dideoxycytidine-5'-Triphosphate (ddCTP) is a sugar modified nucleoside triphosphate, where the 2' and 3' hydroxyl groups are absent, resulting in chain termination.