Dec 21, 2015 · Using wild type or mutated DUSP5 promoter reporters, we demonstrated that SRF plays a crucial role in serum induction of DUSP5 promoter activity, the proximal CArG box …

Dec 21, 2015 · Using wild type or mutated DUSP5 promoter reporters, we demonstrated that SRF plays a crucial role in serum induction of DUSP5 promoter activity, the proximal CArG box …

The current study aimed to clone the DUSP5 promoter, and investigate its transcriptional activity in the presence of quercetin. The results revealed that quercetin-induced DUSP5 expression is …

Recently, it has been suggested that DUSP5 expression is regulated by serum response factor (SRF) and ETS like-1 protein (Elk-1) , and by microRNAs (i.e., miR-95 and miR-32-5p) [20,21]. …

Dual specificity phosphatase 5 (DUSP5), a specific negative feedback regulator of ERK signaling, is controlled by serum response factor (SRF) and Elk-1 transcription factors

Jan 4, 2017 · We demonstrate that the MKP DUSP5 terminates nuclear ERK signaling but, surprisingly, promotes ERK activation in the cytoplasm by relieving feedback inhibition of …

Dec 21, 2015 · Using wild type or mutated DUSP5 promoter reporters, we demonstrated that SRF plays a crucial role in serum induction of DUSP5 promoter activity, the proximal CArG box …

Dec 11, 2017 · Here, we show that DUSP5 is induced during lipopolysaccharide (LPS)-mediated inflammation and inhibits nuclear factor-κB (NF-κB) activity. DUSP5 mRNA and protein …

SRF regulates abundance of Dusp family members. a-c mRNA levels of Dusp1 (a), Dusp5 (b) and Dusp6 (c) in the hippocampus of heterozygous and Srf mutant animals without or with 40 min …

Dual specificity protein phosphatase 5 is an enzyme that in humans is encoded by the DUSP5 gene. [5][6] The protein encoded by this gene is a member of the dual specificity protein …