Dual specificity protein phosphatase 5 is an enzyme that in humans is encoded by the DUSP5 gene. [5][6] The protein encoded by this gene is a member of the dual specificity protein …

Mar 30, 2025 · DUSP5 (Dual Specificity Phosphatase 5) is a Protein Coding gene. Diseases associated with DUSP5 include Epilepsy, Idiopathic Generalized 2 and Lymphoma, Mucosa …

Dec 11, 2017 · Here, we show that DUSP5 is induced during lipopolysaccharide (LPS)-mediated inflammation and inhibits nuclear factor-κB (NF-κB) activity. DUSP5 mRNA and protein …

DUSP5 functions in the feedback inhibition of ERK1/2 signaling in response to TNFalpha, which resulted in increased inflammatory gene expression. Data show that dual specificity …

DUSP5 is a nuclear MKP and inducible by heat shock and growth factors in mammalian cells . DUSP5 binds directly to and inactivates ERK MAPKs, but not other MAPK family members . …

Dec 10, 2024 · Title: DUSP5 suppresses interleukin-1β-induced chondrocyte inflammation and ameliorates osteoarthritis in rats. Integrated analysis identifies DUSP5 as a novel prognostic …

Aug 28, 2003 · Dual-specificity phosphatase 5 (DUSP5), a VH1-like enzyme that hydrolyses nuclear substrates phosphorylated on both tyrosine and serine/threonine residues, has a …

Dec 9, 2016 · DUSP5 is a nuclear, inducible phosphatase with high affinity and fidelity for ERK1/2. By regulating the final step in the MAPK signaling cascade, DUSP5 exerts strong regulatory …

Jul 10, 2021 · DUSP5, a member of DUSPs superfamily, is located in the nucleus and plays crucially regulatory roles in the signaling pathway transduction. In our present study, we …

Dual specificity protein phosphatase 5 (DUSP5) is an enzyme produced by the DUSP5 gene in humans. It belongs to the dual specificity protein phosphatase subfamily, which inactivates …