DNA topoisomerases (or topoisomerases) are enzymes that catalyze changes in the topological state of DNA, interconverting relaxed and supercoiled forms, linked (catenated) and unlinked …

DNA topoisomerases solve the topological problems associated with DNA replication, transcription, recombination, and chromatin remodeling by introducing temporary single- or …

Feb 27, 2023 · Topoisomerase is an essential enzyme that aids in the DNA replication process, segregation of chromosomes, transcription, and also in recombination. It was first found by …

Nov 25, 2023 · Topoisomerases, or DNA topoisomerases, are enzymes that create single or double-stranded nicks in DNA during its replication or transcription to relieve the stress in a …

DNA topoisomerases, capable of manipulating DNA topology, are ubiquitous and indispensable for cellular survival due to the numerous roles they play during DNA metabolism. As we review …

Jun 1, 2002 · DNA topoisomerases are the magicians of the DNA world — by allowing DNA strands or double helices to pass through each other, they can solve all of the topological …

DNA topoisomerases are enzymes that control the topology of DNA in all cells. There are two types, I and II, classified according to whether they make transient single- or double-stranded …

DNA topoisomerases are enzymes that control the topology of DNA in all cells. There are two types, I and II, classified according to whether they make transient single- or double-stranded …

Feb 28, 2022 · In this Review, we discuss their biochemistry and their roles in transcription, DNA replication and chromatin remodelling, and highlight the recent progress made in …

Topoisomerases catalyze strand scission by forming a reversible, covalent enzyme–DNA adduct through their active site tyrosine. Type IB and IC topoisomerases become attached to 3′ DNA …