DNA gyrase, or simply gyrase, is an enzyme within the class of topoisomerase and is a subclass of Type II topoisomerases [1] that reduces topological strain in an ATP dependent manner …

Oct 25, 2024 · Explore the intricate role of DNA gyrase in supercoiling and its interaction with antibiotics and topoisomerases. DNA gyrase is an enzyme in molecular biology that manages …

In assays of DNA gyrase, the introduction of two negative supercoils causes the rotor to spin by two full rotations per enzymatic cycle, while a distal swivel prevents the permanent …

Dec 1, 2024 · DNA gyrase is a member of the DNA topoisomerase protein family that catalyzes the conversion of different topological forms of DNA into one another. It is the sole enzyme …

Aug 3, 2023 · Prokaryotic topoisomerase II, also known as DNA gyrase, is the only topoisomerase that introduces negative supercoils into DNA thus far. DNA topoisomerases are a class of …

Relaxed closed-circular DNA is converted to negatively supercoiled DNA by DNA gyrase. This enzyme has been purified from Escherichia coli cells. The reaction requires ATP and Mg++ …

DNA gyrase is an essential bacterial enzyme that catalyzes the ATP-dependent negative super-coiling of double-stranded closed-circular DNA. Gyrase belongs to a class of enzymes known …

Jan 5, 2006 · DNA gyrase is a molecular machine that uses the energy of ATP hydrolysis to introduce essential negative supercoils into DNA 1, 2, 3. The directionality of supercoiling is …

DNA gyrase modifies DNA topology by introducing negative supercoils, which helps alleviate the torsional strain generated during DNA unwinding. In contrast, helicases unwind the DNA …

DNA gyrase is an essential bacterial enzyme that catalyzes the introduction of negative (−) supercoils into chromosomal and plasmid DNA. Gyrase was discovered soon after it was clear …