Long interspersed nuclear elements (LINEs) [1] (also known as long interspersed nucleotide elements[2] or long interspersed elements[3]) are a group of non-LTR (long terminal repeat) …

LINE1 (an abbreviation of Long interspersed nuclear element-1, also known as L1 and LINE-1) is a family of related class I transposable elements in the DNA of many groups of eukaryotes, …

The repetitive and variable nature of LINE-1 DNA sequences pose unique challenges to studying them, but recent advances in reagents and next generation sequencing present opportunities …

Genetic structure of human and murine LINE1 and SINEs. Short interspersed nuclear elements (SINEs) are non-autonomous, non-coding transposable elements (TEs) that are about 100 to …

During TPRT, the L1 endonuclease (EN) nicks genomic DNA, exposing a free 3′-OH that can serve as a primer for reverse transcription of the L1 RNA. The processes of second-strand …

Long Interspersed Nuclear Element-1 (LINE-1) are DNAs that compromise 17% of our genome. LINE-1 expression is triggered by environmental stressors and accomplished through its …

Since the publication of Mobile DNA II in 2002, much has been learned about the mechanism of LINE-1 and SINE retrotransposition, the impact of these elements on the human genome, and …

Jun 7, 2024 · A CRISPR–Cas9 screen identifies genes that modulate long interspersed nuclear element-1 (LINE-1) expression in human cells.

Feb 1, 2020 · Long interspersed nuclear elements 1 (LINE1) are non-LTR retrotransposons that represent the greatest remodeling force of the human genome during evolution.

Mar 28, 2013 · LINE-1 (L1) retrotransposons make up a significant portion of human genomes, with an estimated 500,000 copies per genome. Like other retrotransposons, L1 …