Feb 18, 2022 · DNA/RNA-gold nanoparticle (DNA/RNA-AuNP) nanoprobes have been widely employed for nanobiotechnology applications. Here, we discover that both thiolated and non-thiolated DNA/RNA can be...

DNA-modified AuNPs (DNA-AuNPs) have exciting features and bright prospects in many fields, which have been intensively investigated in the past decade. In this review, we summarize the various approaches for the immobilization of DNA strands on the surface of AuNPs.

Mar 18, 2025 · DNA-functionalized gold nanoparticles (DNA–AuNPs) and nanorods (DNA–AuNRs) have emerged as key yet versatile biomaterials for applications in biosensing, diagnostics and programmable assembly. The high cost and sometimes complex procedures of functionalization of DNA onto AuNPs and AuNRs via the Au−thiol interactio

Jan 30, 2015 · Monovalent DNA–gold nanoparticle (mDNA–AuNP) conjugates hold great promise for widespread applications, especially the construction of well-defined, molecule-like nanosystems. Previously...

Sep 1, 2020 · DNA-modified gold nanoparticles (AuNPs) are useful nanomaterials for detecting multiple molecules. However, their performance is greatly dependent on the density of probe DNA on the surface of AuNPs.

Apr 22, 2019 · Attaching thiolated DNA to gold nanoparticles (AuNPs) is a highly important and useful reaction for many applications. Various methods such as adding salts, acids, polymers, and surfactants have been developed to facilitate the reaction.

Aug 3, 2021 · Here, we demonstrate that lipoic acid-modified dinucleotides can be used to modify AuNPs surfaces in a controllable manner to produce conjugates that are stable in aqueous buffers and...

Jun 1, 2024 · Engineering DNA-AuNPs enables biosensing of biomolecules for more intuitive and accurate access to spatiotemporal information. Continuous innovation of synthesis enhances the efficiency in designing more functionalized nanomaterials across diverse fields.

DNA-functionalized gold nanoparticles (DNA–AuNPs) have shown great potential and exciting opportunities for constructing machine-like nanodevices. Nonthiolated DNA can be grafted onto gold surfaces via DNA bases, such as polyadenine (polyA)–DNA.

Jan 13, 2014 · Here, we report a class of core–shell complexes (AuNP@DNA cages): hard gold NPs (AuNPs) are encapsulated in geometrically well-defined soft DNA nanocages. The AuNP guest can be further controllably released from the host (DNA nanocages), pointing to potential applications in surface engineering of inorganic NPs and cargo delivery of DNA ...