- Protein Coding geneDDX5 (DEAD-Box Helicase 5) is a Protein Coding gene. Diseases associated with DDX5 include Lung Cancer and Cartilage-Hair Hypoplasia. Among its related pathways are Processing of Capped Intron-Containing Pre-mRNA and SARS-CoV-2 Genome Replication and Transcription.www.genecards.org/cgi-bin/carddisp.pl?gene=DDX5
DDX5 - Wikipedia
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Thi…
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Multiple functions of the DEAD-box RNA helicase, …
DDX5 (p68) is a well-known multifunctional DEAD-box RNA helicase and a transcription cofactor. Since its initial discovery more than three decades ago, DDX5 is gradually recognized as a potential biomarker and target for the …
DDX5 DEAD-box helicase 5 [Homo sapiens (human)]
Feb 9, 2025 · Title: The DEAD-box RNA helicase DDX5 (p68) and β-catenin: The crucial regulators of FOXM1 gene expression in arbitrating colorectal cancer. Splicing factor SRSF3 promotes the progression of cervical cancer through …
DDX5 plays essential transcriptional and post-transcriptional roles …
May 23, 2019 · We demonstrate that DDX5 regulates appropriate splicing of key genes necessary for spermatogenesis. Moreover, DDX5 regulates expression of cell cycle genes in …
- Author: Julien M. D. Legrand, Julien M. D. Legrand, Ai-Leen Chan, Ai-Leen Chan, Hue M. La, Hue M. La, Fernan...
- Publish Year: 2019
DDX5 and DDX17—multifaceted proteins in the regulation of …
DDX5 and DDX17 share the greatest homology among the DDX gene family members. DDX5 and DDX17 are abnormally expressed in many tumors and participate in tumorigenesis, tumor …
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DDX5 - an overview | ScienceDirect Topics
DDX5 is an important helicase which is implicated in many stages of the gene expression pathway including RNA processing (splicing, transport and translation) [1, 2], DNA replication …
Functions of DEAD box RNA helicases DDX5 and DDX17 in …
DDX5 (p68) and DDX17 (p72) belong to the large family of evolutionarily conserved DEAD box RNA helicases (1). Because of their multiple molecular activities, these two proteins have …
1655 - Gene ResultDDX5 DEAD-box helicase 5 [ (human)]
A ubiquitously expressed, androgen-insensitive gene, DDX5, fused in frame with ETV4, leading to the expression of a DDX5-ETV4 fusion protein was identified in prostate cancer. DEAD-box …
Gene: DDX5 (ENSG00000108654) - Summary - Homo_sapiens
View alleles of this gene on alternative sequences. This gene has 34 transcripts (splice variants), 1 gene allele, 5 paralogues and is associated with 35 phenotypes. Show transcript table.
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