Curculin or neoculin is a sweet protein complex that was discovered and isolated in 1990 from the fruit of Curculigo latifolia (Hypoxidaceae). [1] Like miraculin , curculin exhibits taste-modifying activity; however, unlike miraculin, it also exhibits a sweet taste by itself.

Sep 28, 2024 · Curcumin is a bioactive compound and is what gives turmeric its bright color. It was first isolated by scientists around the turn of the 20th Century, and its antibacterial properties were first...

Jul 31, 2023 · Curculin is a sweet protein derived from plants, while curcumin is a natural bioactive compound found in turmeric, a type of ginger. Curcumin is known for its anti-inflammatory and antioxidant properties.

It is revealed that curculin exhibits sweetness and taste-modifying activities through its partially overlapping but distinct molecular surfaces, which are suggested to be involved in the interaction with the sweet taste receptor.

Aug 11, 2015 · Neoculin (NCL) is a heterodimeric protein isolated from the edible fruit of Curculigo latifolia. It exerts a taste-modifying activity by converting sourness to sweetness.

Curculin is a sweet protein that was discovered and isolated in 1990 from the fruit of Curculigo latifolia, [5] a plant from Malaysia. Like miraculin , curculin exhibits taste-modifying activity; however, unlike miraculin, it also exhibits a sweet taste by itself.

A three-dimensional model of curculin, a sweet-tasting and taste-modifying protein from the fruits of Curculigo latifolia, was built from the X-ray coordinates of GNA, a mannose-binding lectin from snowdrop (Galanthus nivalis).

Nov 16, 2007 · Curculin isolated from Curculigo latifolia, a plant grown in Malaysia, has an intriguing property of modifying sour taste into sweet taste. In addition to this taste-modifying activity, curculin itself elicits a sweet taste.

To identify critical sites for these activities, we performed a mutational and structural study of recombinant curculin. Based on the comparison of crystal structures of curculin homo- and heterodimers, a series of mutants was designed and subjected to tasting assays.

Aug 27, 2004 · Curculin from Curculigo latifolia is a unique sweet protein that exhibits both sweet-tasting and taste-modifying activities. We isolated a gene that encodes a novel protein highly homologous to curculin.