The development of a direct and enantioselective, one-pot, three-component cross-Mannich reaction of two different aldehydes is desirable to expand the scope of these powerful …

Apr 7, 2004 · The first proline‐catalyzed direct catalytic asymmetric one‐pot, three‐component cross‐Mannich reaction has been developed. The highly chemoselective reactions between …

Feb 15, 2007 · To expand the scope of these powerful asymmetric Mannich reactions, we have developed a direct and enantioselective, one-pot, three-component, cross-Mannich reaction of …

Jan 5, 2006 · A wide variety of optically active compounds as well as active compounds such as amino acid derivatives can be accessed by the cross-Mannich reaction of aldehydes, …

Aug 7, 2003 · A double-crossed reaction: The use of proline as an organocatalyst enables a one-pot, direct, cross-Mannich reaction to be performed between two different aldehydes and 4 …

Apr 19, 2004 · The first proline-catalyzed direct catalytic asymmetric one-pot, three-component cross-Mannich reaction has been developed. The highly chemoselective reactions between …

The document discusses the development of a direct and enantioselective, one-pot, three-component cross-Mannich reaction of aldehydes, led by Yujiro Hayashi and his team. This …

This protocol describes a procedure for the synthesis of syn-beta-amino alpha-substituted aldehydes, versatile intermediates in synthetic organic chemistry, via asymmetric, direct, one …

To expand the scope of these powerful asymmetric Mannich reactions, we have developed a direct and enantioselective, one-pot, three-component, cross-Mannich reaction of two different …

Apr 7, 2004 · The first proline-catalyzed direct catalytic asymmetric one-pot, three-component cross-Mannich reaction has been developed. The highly chemoselective reactions between …