Cre-Lox recombination is a site-specific recombinase technology, used to carry out deletions, insertions, translocations and inversions at specific sites in the DNA of cells. It allows the DNA …

This review provides a brief overview of Cre-loxP system and a few commonly used promoters for expression of tissue-specific Cre recombinase. Also, we finally introduce some available links …

Cre-loxP recombination allows scientists to excise, insert, or invert specific DNA segments with unprecedented accuracy. This works through two key components: a Cre recombinase and …

Mar 2, 2017 · The cre-loxP-mediated recombination system (the "cre-loxP system") is an integral experimental tool for mammalian genetics and cell biology. Use of the system has greatly …

Here is the most efficient breeding scheme for generating Cre/ lox tissue-specific or inducible knockouts. To generate mice that are heterozygous for a loxP -flanked allele and …

The Cre-lox system, derived from P1 bacteriophage, is a potent and specific system for controlling gene expression. The protein Cre recombinase recognizes 34 bp loxP sites, and the …

The Cre-lox system is a technology that can be used to induce site-specific recombination events. The system consists of two components derived from the P1 bacteriophage: the Cre …

Cre recognizes and recombines pairs of loxP sequences characterized by an inverted repeat and asymmetric spacer. Cre cleaves and religates its DNA targets such that error-prone repair …

Apr 4, 2025 · Emerging literature suggests that the efficiency of Cre-recombination can be influenced by the Cre-driver strain [23, 25] as well as the inter-loxP distance; in mouse …

Mar 14, 2025 · Explore the versatility of Cre-loxP recombination and its role in precise genetic modifications, from inducible systems to spatial and temporal control in research.