The concept of conventional TACE (cTACE) is the selective obstruction of tumor-feeding artery by injection of chemotherapeutic agents, leading to ischemic necrosis of the target tumor via cytotoxic and ischemic effects.

Aug 15, 2024 · Transcatheter arterial chemoembolisation (TACE), also known as transarterial chemoembolisation, is a minimally-invasive method of administering chemotherapy directly to a liver tumor via a catheter under digital subtraction angiography (DSA).

TACE is considered the first-line treatment for patients with intermediate stage HCC. The purpose of this review was to assess the indications, the optimal treatment schedule, the technical factors associated with TACE, and the overall application of TACE as a personalized treatment for HCC.

Transcatheter arterial chemoembolization (TACE) is a proven and widely accepted treatment option for hepatocellular carcinoma and it is recommended as first-line non-curative therapy for BCLC B/intermediate HCC (preserved liver function, multifocal, no cancer-related symptoms) in patients without vascular involvement.

Jul 3, 2023 · Conventional TACE (cTACE) is a mixture of three agents: lipiodol contrast agent, a chemotherapy drug, and an embolization agent. TACE using drug-eluting beads (TACE-DEB or DEB-TACE) uses resin beads that slowly release chemotherapy.

Mar 12, 2025 · In conventional TACE, the chemotherapy drugs are given into the artery. Then, the artery is plugged (embolized). In drug-eluting bead chemoembolization (DEB-TACE), tiny beads with an attached ...

Oct 10, 2023 · Conventional TACE is the most commonly used intra-arterial technique for unresectable ICC. The protocol is the same as for other cancers, and due to the main central location of ICC within the liver, angiographic evaluation of both the right and the left hepatic arteries is required to ensure selective treatment of the tumour-feeding vessels ...

4 days ago · Transarterial chemoembolization (TACE) remains the gold standard for treating intermediate-stage hepatocellular carcinoma (HCC), yet faces great challenges in overcoming tumor heterogeneity, hypoxia-induced angiogenesis, and metastatic progression. ... emphasizing the limitations of conventional approaches and innovations in flexible embolic ...

21 hours ago · The decision to use conventional TACE (cTACE) or drug eluting beads (DEB)-TACE is made by the interventional radiologist. Patients in previous clinical trials all received DEB-TACE. All TACE procedures were performed by experienced interventional radiologists, they all have more than 10 years of experience in interventional radiology.

Feb 22, 2016 · Conventional transarterial chemoembolization (TACE) is an internationally accepted and globally applied therapy for the treatment of surgically unresectable intermediate stage (Barcelona Clinic Liver Cancer [BCLC] stage B) hepatocellular carcinoma (HCC) [1].