Nov 6, 2021 · Magnetic resonance imaging (MRI) depicts intrinsic contrast between structures using differences in magnetization properties, but it was recognized early in the development of MRI that paramagnetic agents enhance tissue discrimination. 1-3 Gadolinium (Gd) was shown to have a particularly strong effect on shortening the T1 and T2 relaxation ...

Nov 2, 2024 · Contrast enhancement in MRI relies on introducing contrast agents that alter the magnetic properties of tissues, allowing for improved image contrast and resolution. These agents are typically paramagnetic, meaning they possess unpaired electrons that influence the magnetic field within the MRI scanner.

Feb 8, 2023 · Contrast enhancement is a ubiquitous term in radiology and can be used in three ways. Firstly, it may refer to any method of exaggerating the visible difference between adjacent structures on imaging by administering contrast media/agents. This includes differentiating between normal structures.

Jan 25, 2016 · Advances in contrast media and the technical capabilities of MRI have increased the accuracy and utility of contrast-enhanced-MRI (CE-MRI) for many different indications. Today, CE-MRI is a valuable and established diagnostic imaging tool worldwide, used annually in approximately 30 million procedures, with more than 300 million procedures ...

Mar 1, 2014 · Studies assessing this effect are commonly termed Dynamic Contrast Enhanced (DCE)- MRI, T1-W DCE or Dynamic Relaxivity MRI. It is known from conventional MRI, that on the boundaries between structures that differ in their magnetic susceptibility, local magnetic inhomogeneities arise.

Feb 7, 2024 · Unlike MRI that is enhanced by gadolinium-based contrast agents, FE-MRI offers advantages such as reduced contrast agent dosage, extended imaging windows, no nephrotoxicity, higher MRI time efficiency and the capability for molecular imaging.

Feb 7, 2024 · Contrast-enhanced magnetic resonance imaging (CE-MRI) is a pivotal tool for global disease diagnosis and management. Since its clinical availability in 2009, the off-label use of ferumoxytol for ferumoxytol-enhanced MRI (FE …

This review aims to provide an overview on the history of MRI and contrast media development, to highlight certain key advances in the clinical development of CE-MRI, to outline current technical trends and clinical challenges, and to suggest some important future perspectives.

Today, after 25 years of contrast-enhanced (CE-) MRI in clinical practice, the utility of this diagnostic imaging modality has expanded beyond initial expectations to become an essential tool for disease diagnosis and management worldwide.

5 days ago · The combination of contrast-enhanced CT and MRI demonstrated a statistically significant improvement in sensitivity (90.6% for MRI alone vs. 96.5% for combined modalities) and specificity (95.3% for MRI alone vs. 98.3% for combined modalities). Positive and negative predictive values were similarly enhanced. Radiologists’ diagnostic ...