We report a simple and reliable identification of mouse serum protein (for instance, see Figure 5) and as shown in Table 1, our work evidences an improved identification when compared with previous studies based on pre-treatments of serum or other sophisticated methods.

Results: A 7-lectin LeMBA-MS/MS discovery screen shortlisted 59 candidate proteins and three lectins. Validation analysis using 3-lectin LeMBA-multiple reaction monitoring (MRM) confirmed elevated A1AT, AACT, CO9, HPT and ITIH3 and reduced A2MG, ALS, IBP3 and PON1 glycoforms in HGSOC.

Aug 24, 2022 · Results showed that the DEPs, including CO9, LBP, SVEP1, and VWF levels in extracellular vesicles (EVs) were significantly higher in CHB than in healthy controls (HCs). VWF expression levels in...

Results: We identified 95 differentially expressed proteins (50 up-regulated and 45 down-regulated), and selected nine proteins (α-enolase (ENOA), glyceraldehyde-3-phosphate dehydrogenase (G3P), complement component C9 (CO9), profilin-1 (PROF1), lipopolysaccharide-binding protein (LBP), tubulin beta-4A chain (TBB4A), phosphoglycerate kinase ...

Mar 28, 2025 · C9 (Complement C9) is a Protein Coding gene. Diseases associated with C9 include Complement Component 9 Deficiency and Macular Degeneration, Age-Related, 15. Among its related pathways are Complement cascade and Immune response Lectin induced complement pathway. An important paralog of this gene is C8A.

Feb 21, 2017 · Here, we report an unbiased and in-depth analysis of the complement component C9 protein isolated from pooled human blood serum (of at least three donors) using modern, hybrid MS technologies. Our data provides a detailed view of …

2 Proteoform profile mapping of the human serum Complement component C9 3 reveals unexpected new features of N-, O- and C-glycosylation 4 5 Vojtech Franc 1,2, Yang Yang , and Albert J.R. Heck1,2* 6 1 Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research

Dec 5, 2022 · The combination of plasma exosomal proteins A0A0G2JRQ6, C1QC, CO9, GP1BB, RSU1, and ADA10 acts as a novel candidate biomarker to differentiate AD patients from healthy individuals.

Jun 1, 2023 · A 7‐lectin LeMBA‐MS/MS discovery screen shortlisted 59 candidate proteins and three lectins. Validation analysis using 3‐lectin LeMBA‐multiple reaction monitoring (MRM) confirmed elevated A1AT, AACT, CO9, HPT and ITIH3 and reduced A2MG, ALS, IBP3 and PON1 glycoforms in HGSOC.

Oct 22, 2024 · PXD032299 is an original dataset announced via ProteomeXchange. We aimed to discover and validate a panel of serum biomarkers for high grade serous ovarian cancer (HGSOC) using our lectin-magnetic bead array-coupled proteomics platform.