CHO-K1 cell line was derived as a subclone from the parental CHO cell line, which was initiated from a biopsy of an ovary of an adult, female Chinese hamster in 1957. The cell line is used for industrial biotechnology and toxicology research.

Nov 20, 2023 · Understanding the differences between CHO S and CHO K1 is important for selecting the correct cell line based on specific experimental requirements. This content outline will explore the characteristics, genetic background, growth properties and applications of CHO-S versus CHOK1 cell lines.

Aug 3, 2023 · CHO (Chinese hamster ovary) cells refer to a cell line derived from the ovary of the Chinese hamster. In contrast, CHO-K1 cells refer to a cell line isolated from the ovary of an adult female Chinese hamster that can be used in industrial biotechnology and toxicology research.

CHO-K1 cells are derivative of the Chinese hamster ovary (CHO) cell line. They are extensively used in industrial biotechnology to produce biopharmaceutics and other recombinant proteins. Besides, the CHO-K1 cell line is also employed in toxicology research.

The CHO-K1 cell line was derived as a subclone from the parental CHO cell line initiated from a biopsy of an ovary of an adult Chinese hamster by T. T. Puck in 1957. The cells require proline in the medium for growth. ATCC CCL-61. Maintaining healthy cells is the key to experimental success and reproducible research results.

Sep 15, 2023 · CHO细胞 (Chinese Hamster Ovary cells，中国仓鼠卵巢细胞)是一种来源于中国仓鼠卵巢细胞的实验室培养细胞系。 中国仓鼠于1948年被带到美国，1957年，T.Puck从波士顿癌症研究基金会的实验室获得了一只中国仓鼠，在那里他用它获得了原始的CHO细胞系。 从那时起，人们发现CHO细胞在许多研究中都很有用。 在60多年的CHO细胞研究历史中，从原始细胞系衍生出多种具有不同属性的不同细胞系。 常见的CHO衍生物是CHO-K1。 它于1957年诞生，是 …

CHO-K1 is an adherent line and was traditionally grown of F12 Medium supplemented with 10% FBS. The CHO lines were thought to be important because they had few chromosomes for a mammalian cell and were used for radiation cytogenetics and they were known for their ease of …

Chinese hamster ovary (CHO) cells comprise a variety of lineages including CHO-DXB11, CHO-K1, CHO-DG44, and CHO-S. Despite all CHO cell lines sharing a common ancestor, extensive mutagenesis, and clonal selection has resulted in substantial genetic heterogeneity among them.

Feb 10, 2025 · Explore the genetic and morphological nuances of CHO-K1 cells, highlighting their unique biological characteristics and cellular processes. Chinese Hamster Ovary (CHO) cells, …

May 15, 2020 · We are excited to announce that the significantly improved Chinese hamster genome, CH PICR (GCF_00366804.1), along with its 2018 RefSeq annotation is now online. In addition, an updated RefSeq annotation for the CHO-K1 cell line is now available. Both can be searched (gene search and BLAST) and viewed on JBrowse.