Dec 11, 2024 · Developmental Cell publishes peer-reviewed articles within and at the interface of cell biology and developmental biology.

Cells & Development is an international journal covering the areas of cell biology and developmental biology. In addition to publishing work at the interphase of these two disciplines, we also publish work that is purely cell biology as well as classical developmental biology.

Jun 20, 2024 · We describe how classic questions in gene regulation, pattern formation, morphogenesis, organogenesis, and stem cell biology are being revisited. We discuss the connections of development with evolution, self-organization, metabolism, time, and ecology.

Sep 8, 2021 · We describe the early milestones that have been achieved and the use of human stem-cell-derived cultures, organoids and animal models to inform the HDCA, especially for prenatal tissues that...

Mar 20, 2025 · Ambrosi and colleagues profile human skeletal stem cells (hSSCs) across ten fetal skeletal sites and from patients throughout adulthood, identifying, mapping, and functionally testing four distinct hSSC subtypes. Skeletal aging and disease are characterized by a dominant fibrogenic hSSC variant, but targeting defined gene regulatory networks reinstates functional hSSC diversity.

Mar 4, 2025 · Background Single-cell multi-omics technologies, particularly single-cell RNA sequencing (scRNA-seq), have revolutionized our understanding of cellular heterogeneity and development by providing insights into gene expression at the single-cell level. Investigating the influence of genes on cellular behavior is crucial for elucidating cell fate determination and differentiation, cell ...

This issue provides an update of new and exciting developments in the field of cell dynamics and covers a broad range of experimental approaches to study diverse aspects of cell migration, cell polarity, and cell-cell and cell-substrate interactions.

During development, controlled differentiation programmes give rise to a broad repertoire of cells with highly specialised functions and tissue locations. The Human Developmental Cell Atlas (HDCA) aims to generate a comprehensive profile of …

Understanding how organisms develop requires a systems-level understanding of how cells achieve different fates, and what combinations of intercellular signaling and intracellular regulatory circuits generate spatially and temporally encoded patterns along the body axis.

Early development is characterized by the rapid proliferation of embryonic cells, which then differentiate to produce the many specialized types of cells that make up the tissues and organs of multicellular animals.