What is Epicel? Epicel is a type of graft made from a patient's own skin. It is also called "Cultured Epidermal Autograft" or "CEA." These grafts provide a permanent skin replacement for patients with deep dermal or full thickness burns.

Epicel (cultured epidermal autografts) is authorized for use in adult and pediatric patients who have deep dermal or full thickness burns comprising a total body surface area greater than or equal to 30%.

Skin graft base underlay (STSG) is recommended for use with CEA. One hundred percent (100%) of surgeons indicated they use a skin graft underlay for Epicel (11% RECELL, 33% STSG [4:1], 67% STSG [6:1], and 0 use MEEK).

Split-thickness skin (STSG) autografts are the "gold standard" for burn wound closure and remain the mainstay of treatment to provide permanent wound coverage and achieve healing. In some massively burned patients, however, the burns are so extensive that donor site availability is …

Jun 1, 2007 · Split-thickness skin (STSG) autografts are the “gold standard” for burn wound closure and remain the mainstay of treatment to provide permanent wound coverage and achieve healing. In some massively burned patients, however, the burns are so extensive that donor site availability is limited.

Epicel (cultured epidermal autografts) is authorized for use in adult and pediatric patients who have deep dermal or full thickness burns comprising a total body surface area greater than or equal to 30%.

The wounds were treated with cultured epithelial autograft (CEA) and laid over a 4:1 meshed autologous split-thickness skin graft. This technology played a vital role in allowing the patient to survive a massive burn injury and achieve a reasonable quality of life (Figure 1). 1

Cultured keratinocytes provide an excellent alternative or adjunct to conventional split-thickness skin grafting in treating large burn wounds. A dedicated team of physicians, nurses, and therapists well rehearsed in CEA care are vital for success in keratinocyte grafting.

Cultured epithelial autografts (CEA) have been clinically utilized since 1981 & can be a lifesaving procedure in patients with extensive full thickness burns. CEA is more susceptible to bacterial contamination & complete graft loss than traditional split-thickness autografts, yet no standard of practice exists for the postoperative care of ...

To assess the efficacy of cultured epidermal autografts (CEA) for closure of burn wounds in pediatric burn patients with full-thickness burns of more than 90% total body surface area. Paucity of donor sites in massive burns makes the use of expanded skin of paramount importance.