CD7 (C luster of D ifferentiation 7) is a protein that in humans is encoded by the CD7 gene. [5] This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells.

Mar 28, 2025 · CD7 (CD7 Molecule) is a Protein Coding gene. Diseases associated with CD7 include Mycosis Fungoides and Lymphoblastic Lymphoma. Among its related pathways is Innate Lymphoid Cells Differentiation. Gene Ontology (GO) annotations related to this gene include signaling receptor activity.

Dec 17, 2008 · In terms of character, the CD7 is essentially neutral, but its range of tonal colour and harmonic development mean that it tends toward the rich and full bodied rather than lean and emaciated, while the top end is beautifully sweet and capable of real articulation where required.

May 13, 2021 · Binds galectin 1 and is essential for galectin 1 mediated T cell death; loss of CD7 expression and altered cellular glycosylation may contribute to apoptosis resistance in mycosis fungoides (Mod Pathol 2003;16:543)

Mar 1, 2003 · CD7 identifies three populations of CD8 T cells: CD7 high (CD7 (high)), low (CD7 (low)), and negative (CD7 (neg)) that translate into subsets with distinct functional properties. The CD7 (high) subset contains naive and memory cells and the CD7 (low) and CD7 (neg) subsets contain effector cells.

Apr 24, 2024 · Our findings suggest that sequential CD7 CAR T-cell therapy and haploidentical HSCT is safe and effective, with remission and serious but reversible adverse events. This strategy offers a...

CD7 is a T-cell antigen that is expressed in a small percentage of individuals with AML. Somatic cell hybridization was used to localize the CD7 gene to chromosome 17 [6]. In most studies, CD7 is the most prevalent aberrant marker in AML.

CD7 CD7 has the distinction of being the most frequently lost T-subset marker in malignancies, particularly on mycosis fungoides.39 It is also present on non-T-cell malignancies, including NK tumors and acute myeloid leukemia. It is detectable on paraffin sections only with difficulty.

CD7 is a single-domain Ig superfamily molecule expressed on human T and NK cells, as well as on cells in the early stages of T, B, and myeloid cell differentiation. CD7 is highly expressed on malignant immature T cells and is generally absent on malignant mature T cells, such as CD4+ Sezary leukemia …

The CD7 molecule is a membrane-bound glycoprotein of 40 kD and is the earliest T cell specific antigen to be expressed in lymphocytes. CD7 antigen is also the only early marker to persist throughout differentiation.