Jul 7, 2011 · In CD48-null mice, the resultant misregulation of cytokine signaling produces a more quiescent HSC, a disproportionate number of short-term progenitors, and hyperactivation of …

Jul 3, 2013 · Here we show that four SLAM family markers, CD150, CD48, CD229, and CD244, can distinguish HSCs and MPPs from restricted progenitors and subdivide them into a …

Sep 12, 2017 · LSK cells can be subfractionated, based on their expression of SLAM family markers (i.e., CD150 and CD48), into LT-HSCs (HSC: CD150 + CD48 − LSK), MPP (CD150 − …

Aug 3, 2022 · Immunophenotypic HSCs (lineage – Sca-1 + CD117 + (LSK) CD48 −/lo CD150 +; Supplementary Fig. 1) are a heterogeneous population with regard to proliferative activity, …

Dec 1, 2022 · Combinations of the SLAM markers (CD150 and CD48), CD34 and/or CD135 have now been used to further purify HSC and MPP populations within lineage-negative, c-KIT+, …

Jul 24, 2018 · Hematopoietic stem cells (HSCs) are the source of both normal blood cells and leukemia [1]. The ability to identify and purify them using multiple surface markers, such as …

Jul 1, 2005 · Cell surface receptors of the SLAM family, including CD150, CD244, and CD48, were differentially expressed among functionally distinct progenitors. HSCs were highly …

In this analysis of CD48 and CD150 HSC detection (Figure 2A-C), we noticed that CD48 was more highly expressed in NOD- scid and NSG mice than in C57BL/6 mice as revealed by …

Jun 26, 2012 · Here, we will review and compare major strategies for identifications of HSC as KLS-CD34 − Flk-2 − (1), KLS-CD150 + CD48 − cells (2), the Hoechst-effluxing side population …

Jul 15, 2006 · Adult HSC purity recently has been enhanced using the SLAM family receptors CD150, CD244, and CD48. These markers are expressed at different stages of the …