
Understanding CD30 biology and therapeutic targeting: a ... - Nature
Sep 8, 2017 · CD30 ligand (CD30L, also known as TNFSF8 or CD153) is a membrane-bound cytokine with sequence homology to other members of the tumor necrosis factor (TNF) family. …
CD30 - Wikipedia
CD30, also known as TNFRSF8 (TNF receptor superfamily member 8), [5] is a cell membrane protein of the tumor necrosis factor receptor family and a tumor marker for anaplastic large cell …
Targeting CD30/CD30L in Oncology and Autoimmune and …
Increased CD30L expression was found on mast cells within HD tumors and preclinical and clinical studies with compounds targeting the CD30/ CD30L system in HD and ALCL …
CD30: from basic research to cancer therapy - PMC
The results suggest that CD30L/CD30 signaling is involved in the development of both OXA- and TNBS-induced colitis and that the modulation of CD30L/CD30 signaling by mAb could be a …
Comparison of CD30L and OX40L Reveals CD30L as a Promising …
Nov 26, 2024 · Results: Analysis of several scRNA-seq datasets from skin lesions of AD patients showed that transcripts for CD30 or CD30L were found expressed with OX40 or OX40L in the …
The Polyvalent Role of CD30 for Cancer Diagnosis and Treatment
CD30 engages in various biological processes by interacting with its ligand CD30L (also known as CD153). This interaction gives rise to numerous functions, as described below. CD30 is a …
CD30 Ligand - an overview | ScienceDirect Topics
CD30 Ligand is a type II membrane glycoprotein expressed on various immune cells, such as activated T cells, B cells, and macrophages. It plays a role in regulating the growth and …
Deciphering CD30 ligand biology and its role in humoral immunity
In this review we consider the reported biology of CD30L and focus on results from several recent studies that point to an important role for CD30/CD30L interactions in humoral immune …
CD30L/CD30 signaling regulates the formation of the tumor ... - PubMed
In this study, we established an AOM/DSS-induced CAC model with CD30LKO mice to explore the effect of CD30L/CD30 signal transduction on the formation of the intestinal tumor immune …
Targeting CD30/CD30L in oncology and autoimmune and inflammatory ...
The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in …