Administration of an antibody against apoptosis inhibitor of …
Jul 10, 2024 · In apolipoprotein E-deficient mice, AA was induced by subcutaneous angiotensin II infusion. Mice were randomly divided into two groups: (i) AIM group; weekly anti-murine AIM …
Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas
Two of the studies of mouse aortic leukocytes 5, 106 used CyTOF to characterize the immune cell landscape of Apoe −/− mouse aortas. Each study used 35 markers, 33 of which were …
Circular RNA Cdyl promotes abdominal aortic aneurysm …
The maximal outer diameter of the abdominal aorta from mice in the Sh-circCdyl group was significantly smaller than that of mice in the Scr-RNA group (Figure 2D). Histological analysis …
Critical role of CD206+ macrophages in promoting a cDC1-NK …
Oct 31, 2023 · We thus made a novel conditional CD206 (Mrc1) knock-in mouse to specifically visualize and/or deplete CD206+ ‘M2-like’ TAMs and assess their correspondence with pro …
Bone marrow-derived and peritoneal macrophages have different ...
Oct 13, 2016 · Whole aorta flow cytometry showed an accumulation of M2-like CD206 high CD11c low macrophages in advanced versus early atherosclerotic disease in ApoE−/− mice. …
Targeting CD206+ macrophages disrupts the establishment of a …
Nov 27, 2024 · CD206+ TAMs differentially attracted activated CD8 T cells, and the NK and CD8 T cells in CD206-depleted tumors were deficient in Cxcr3 and cDC1-supportive Xcl1 and Flt3l …
Administration of anti-inflammatory M2 macrophages suppresses ...
Jan 25, 2023 · PKH26-labeled M2Ms accounted for 6.5% of cells in the aneurysmal site and co-expressed CD206. Taken together, intraperitoneal administration of M2Ms inhibited AA …
CD206 + M2-like macrophages regulate systemic glucose
Aug 18, 2017 · We show that adipose tissue CD206 + cells are primarily M2-like macrophages, and ablation of CD206 + M2-like macrophages improves systemic insulin sensitivity, which …
Prolonged Infusion of Angiotensin II in apoE−/− Mice Promotes ...
Sep 1, 2011 · Aortic aneurysmal segments that expanded during continuous AngII infusion exhibited macrophage accumulation in regions of medial disruption, predominantly on the …
atherosclerotic plaques of Ldlr−/− mice using scRNA-seq. The macrophage subset expressing the highest Lyve1 levels of all aortic CD45+ cells also expressed increased levels of mRNA for …
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