CD16 - Wikipedia
CD16 is the type III Fcγ receptor. In humans, it exists in two different forms: FcγRIIIa (CD16a) and FcγRIIIb (CD16b), which have 96% sequence similarity in the extracellular immunoglobulin …
CD16b: Primary Structure of Human Neutrophil Antigen Epitopes and …
Dec 2, 2016 · Neutrophil specific Fcg receptor IIIb (CD16b) is a glycosylphosphatidylinositol-anchored low-affinity glycoprotein that plays a significant role in phagocytosis and the …
ADAM17 cleaves CD16b (FcγRIIIb) in human neutrophils - PMC
CD16b (FcγRIIIb) is exclusively expressed by human neutrophils and binds IgG in immune complexes. Cell surface CD16b undergoes efficient ectodomain shedding upon neutrophil …
NK cell CD16 surface expression and function is regulated by a ...
The second type, CD16B, is found on neutrophils. Although the extracellular domains are highly homologous, glycosylphosphatidylinositol linkage differentiates CD16B from CD16A. Most …
FcγRIIIb Restricts Antibody-Dependent Destruction of Cancer …
Jan 30, 2019 · The function of the low-affinity IgG-receptor FcγRIIIb (CD16b), which is uniquely and abundantly expressed on human granulocytes, is not clear. Unlike the other Fcγ receptors …
CD16b: Primary Structure of Human Neutrophil Antigen
Dec 2, 2016 · Neutrophil specific Fcg receptor IIIb (CD16b) is a glycosylphosphatidylinositol-anchored low-affinity glycoprotein that plays a significant role in phagocytosis and the …
Primary structure of human neutrophil antigens 1a and 1b
Neutrophil specific Fcγ receptor IIIb (CD16b) is a low-affinity IgG receptor. Its polymorphic variants are associated with human neutrophil antigens (HNA). HNA-1a and HNA-1b differ in …
Identification of an ADAM17 Cleavage Region in Human CD16 …
CD16a and CD16b are IgG Fc receptors expressed by human natural killer (NK) cells and neutrophils, respectively. Both CD16 isoforms undergo a rapid down-regulation in expression …
CD16b associates with high-density, detergent-resistant ... - PubMed
Jan 1, 2006 · Altogether, the results of this study provide evidence that high-density DRMs play a role in CD16b signalling in human neutrophils. CD16b is unique in that it is the only Fc …
CD16 is indispensable for antibody-dependent cellular ... - Nature
Sep 27, 2016 · We found that human CD16− expressing monocytes have a broad spectrum of ADCC capacities and can kill cancer cell lines, primary leukemic cells and hepatitis B virus …