CCDC134 serves a crucial role in embryonic development - PMC
Coiled-coil domain containing 134 (CCDC134), a characterized secreted protein, may serve as an immune cytokine and illustrates its potent antitumor effects by augmenting CD8+ T-cell …
Ccdc134 deficiency impairs cerebellar development and motor ...
Aug 21, 2021 · Selective deletion of Ccdc134 in mouse neural stem cells (NSCs) caused defects in cerebellar morphogenesis, including a decrease in the number of PCs and impairment of …
COILED-COIL DOMAIN-CONTAINING PROTEIN 134; CCDC134
Mar 15, 2022 · By participating in the PCAF complex, CCDC134 regulated acetyltransferase activity of ADA2A and inhibited p53 (191170) acetylation and p53-induced apoptosis. …
Ccdc134 deficiency impairs cerebellar development and motor ...
Aug 12, 2021 · Ablation of CCDC134 expression in NSCs results in disruption of cerebellar morphogenesis, including a decrease in the number of PCs and impairment of its dendritic …
ALKBH5-mediated m6A modification of circCCDC134 facilitates
Aug 26, 2022 · CircCCDC134 upregulation in CC was fine-tuned by ALKBH5-mediated m6A modification, which enhanced its stability in a YTHDF2-dependent manner. The functional …
Enhancer variants associated with Alzheimer’s disease affect gene ...
Sep 9, 2019 · We found that rs7364180 significantly interacted with CCDC134 and its adjacent genes MEI1 and SREBF2 (Additional file 3: Figure S4A); however, no long-range chromatin …
CCDC134 interacts with hADA2a and functions as a regulator
May 30, 2012 · Here, we report that coiled-coil domain containing 134 (CCDC134), a novel nuclear protein, binds to hADA2a and enhances the stability of the hADA2a protein in …
Coiled-Coil Domain-Containing (CCDC) Proteins: Functional Roles …
May 3, 2021 · CCDC134 is an efficient biomarker for gastric cancer, since its levels are significantly low in this cancer [86]. CCDC80 inhibits extracellular-regulated protein kinase ½ …
CCDC134 serves a crucial role in embryonic development
Coiled-coil domain containing 134 (CCDC134), a characterized secreted protein, may serve as an immune cytokine and illustrates its potent antitumor effects by augmenting CD8+ T-cell …
CCDC134 - Coiled-coil domain-containing protein 134 - Homo …
In extracellular secreted form, promotes proliferation and activation of CD8 + T cells, suggesting a cytokine-like function (PubMed: 25125657). Enhances cytotoxic anti-tumor activity of CD8 + T …