WSB1 regulates c-Myc expression through β -catenin signaling …
In this study, we found that WSB1, which has a highly positive correlation with c-Myc in 10 cancer cell lines and clinical samples, is a direct target gene of c-Myc, and can positively regulate c …
Wnt/β-catenin signaling pathway upregulates c-Myc expression …
The results showed that SB216763 induced the nuclear translocation of β-catenin, upregulated the expression of c-myc and pluripotency related genes, oct4, sox2 and nanog, and blocked …
β-catenin regulates c-Myc and CDKN1A expression in breast
In this study, we found that c-Myc is highly expressed in the basal-like subtype by microarray analyses and immunohistochemical staining. After silencing β-catenin using siRNA, c-Myc …
Favorable prognosis in colorectal cancer patients with co …
Interestingly, co-expression of c-MYC and ß-catenin—in other words, c-MYC overexpression via ß-catenin—was an independent improved prognostic factor in both the consecutive and …
β-catenin regulates c-Myc and CDKN1A expression in breast …
To understand how β-catenin regulates c-Myc expression in breast cancer, we examined c-Myc mRNA and protein expression after knocking down β-catenin using siRNA transfection. c-Myc …
Molecular Pathogenesis of Chronic Wounds: The Role of β-Catenin and c ...
Here we show that β-catenin and its downstream targets in keratinocytes, c-myc, and keratins K6 and K16, play important roles in the development of chronic wounds. In contrast to normal …
WNT/β-catenin-suppressed FTO expression increases m6A of c-Myc …
May 8, 2021 · In this study, we demonstrate that Wnt signaling induces complex formation between the histone methyltransferases EZH2 and β-catenin, which bind to the promoter …
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to …
Wnt/β‐catenin signalling is emerging for its role in the regulation of ammonia metabolizing enzymes and autophagosome synthesis through c‐Myc. Here, using Huh7 cell line, we show a …
MEIS1 knockdown upregulates WNT signaling pathway genes in …
3 days ago · Then, in the nucleus β-catenin interacts with transcription factors, LEF-1/TCF7, to regulate the expression of pathway target genes such as c-MYC and cyclin D1. As a …
Cell Proliferation | Cell Biology Journal | Wiley Online Library
2 days ago · Enhances the stability of IGF2BP1, c-Myc and E2F1. Facilitates the c-Myc/MNX1-AS1/IGF2BP1 complex to accelerate cell cycle progression and promote lung cancer cell …