Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger, or cellular signal occurring within cells, that is important in many …

In a cAMP-dependent pathway, the activated G s alpha subunit binds to and activates an enzyme called adenylyl cyclase, which, in turn, catalyzes the conversion of ATP into cyclic adenosine …

Regulation of transcription by PKA is mainly achieved by direct phosphorylation of the transcription factors cAMP-response element-binding protein (CREB), cAMP-responsive …

Mar 6, 2022 · Adenylate cyclase (AC) converts adenosine triphosphate (ATP) into cAMP, which stimulates cAMP-dependent protein kinase A (PKA). Subsequently, specific proteins are …

A reduction of cellular ATP content and a corresponding increase in AMP levels (high AMP/ATP ratio) results in an activation of AMPK, which restores the energy balance by inhibiting …

Jan 12, 2025 · Cyclic Adenosine Monophosphate, abbreviated as cAMP, is a crucial cell signaling molecule involved in various physiological processes. It acts as a secondary messenger in …

Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine …

Mar 4, 2009 · We demonstrate for the first time the existence of a CO 2-HCO 3 −-sAC-cAMP-PKA (mito-sAC) signaling cascade wholly contained within mitochondria, which serves as a …

Jan 23, 2020 · We report a mechanism of adenosine triphosphate (ATP) to cyclic adenosine monophosphate (cAMP) conversion by the mammalian type V adenylyl cyclase revealed in …

Jan 1, 2021 · Two separate cAMP signalling systems operate in the core and at the surface of mitochondria. The domestic cAMP signalling machinery appears evolutionary ancient but is …