To assess the interferon response in Caki-1 cells, and therefore their suitability as a good infection model for SARS-CoV-2, we stimulated them with Poly I:C and LPS and measured their IFNα/β output by HEK-Blue IFNα/β assay (Fig. 5C).

COSMIC CELL LINE COSMIC (Catalogue Of Somatic Mutations In Cancer) is an online database of somatically acquired mutations found in human cancer. Especially in the Cell Lines Project, …

Caki-1 is a cell line with epithelial morphology that was isolated from kidney tissue obtained from a 49-year-old, White, male patient with clear cell carcinoma. This cell line is a suitable transfection host and has applications in cancer and toxicology research.

Nov 27, 2023 · Our study found that miR-30e-5p is a key downregulated miRNA in cAKI. The downregulated miR-30e-5p promotes AKI progression by targeting Galnt3 to activate the AMPK signaling pathway. The newly developed MMA NPs were found to have protective effects on cAKI, suggesting a potential novel strategy for preventing cAKI.

Established from a tumor located in the wall of the renal vein of a male patient, Caki-1 cells are commonly used in the study of renal cancer biology, especially in understanding the mechanisms underlying clear cell renal cell carcinoma (ccRCC).

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Caki-1 is a human clear cell renal cell carcinoma (ccRCC) line that displays epithelial morphology and grows in adherent culture. When grown on transwell filters, these cells form a polarized monolayer with microvilli on the apical surface and display characteristic features of the proximal tubule epithelium.

We used RNA sequencing (RNA-Seq) technology to investigate changes in the transcriptome profile in the Caki-1 clear cell renal cell carcinoma (ccRCC) cells, which overexpress monocyte chemoattractant protein-induced protein 1 (MCPIP1).

Kidney carcinoma General information STR profile CellDive-ID 731 DSMZ ACC-731 Cell line name CAKI-1 SpeciesHomo sapiens (human) Cell type kidney carcinoma Incubation medium 80% McCoyïs 5a + 20% h.i. FBS Morphology epithelioid cells growing adherently in monolayers Tumour type - RNA-seq project - Help

CAKI-1 - Cell line: CAKI-1 DSMZ no.: ACC 731Species: human (Homo sapiens)Cell type: kidney carcinoma Origin: established in 1971 from the cutaneous metastasis of the kidney adenocarcinoma of a 49-year