CaCoN2 crystallizes in the triclinic P1 space group. The structure is three-dimensional. there are eight inequivalent Ca2+ sites. In the first Ca2+ site, Ca2+ is bonded to four N3- atoms to form a mixture of distorted corner and edge-sharing CaN4 trigonal pyramids.

Apr 30, 2020 · CaCoN2 crystallizes in the triclinic P1 space group. The structure is three-dimensional. there are eight inequivalent Ca2+ sites. In the first Ca2+ site, Ca2+ is bonded to four N3- atoms to form a mixture of distorted corner and edge-sharing CaN4 trigonal pyramids.

Caco-2 [Caco2] is an adherent cell line isolated from colon tissue derived from a patient with colorectal adenocarcinoma. These cells express characteristics of enterocytic differentiation upon confluence and are a commonly used line for mimicking the small intestine in …

Although the colonic cell line Caco-2 is widely used as a model of the small intestinal barrier function, it has limitations such as overestimated transepithelial electrical resistance (TEER) compared to in vivo conditions. Therefore, we investigated Human Intestinal Epithelial Cells (HIECs) as an alternative in vitro model.

Proper testing of the cell monolayer is absolutely critical in exploiting Caco-2 cells to measure interaction, uptake and cellular transport of drugs and food components. 10.1. Origin. Back in the 1970s several epithelial cell lines were established from gastrointestinal tumors.

Caco-2 (from Cancer coli, "colon cancer") is an immortalized cell line of human colorectal adenocarcinoma cells. It is primarily used as a model of the intestinal epithelial barrier. [1] . In culture, Caco-2 cells spontaneously differentiate into a heterogeneous mixture of intestinal epithelial cells. [1] .

Due to this, a variety of cloned Caco-2 cell lines has been established, and described in the literature. This chapter will however, focus on describing how to handle and cultivate the original Caco-2 cell line as obtained from cell culture collections like American Type Culture Collection and the European Collection of Cell Cultures.

Human Caco-2 cells transfected with c-Ha-Ras as a model for endocrine differentiation in the large intestine.

Different cell line models used in the drug permeability studies, their characteristics has been summarized emphasizing on CACO-2.

“Materials Data on CaCoN2 by Materials Project” is a paper by published in 2020. It has an Open Access status of “closed”. You can read and download a PDF Full Text of this paper here.