CXCL13 is a small chemokine belonging to the CXC chemokine family. As its other names suggest, this chemokine is selectively chemotactic for B cells belonging to both the B-1 and B …

CXCL13 is a chemokine that plays an important role in the regulation and development of secondary lymphoid organs. CXCL13 is also involved in the regulation of pathological …

Mar 30, 2025 · CXCL13 (C-X-C Motif Chemokine Ligand 13) is a Protein Coding gene. Diseases associated with CXCL13 include Angioimmunoblastic T-Cell Lymphoma and Central Nervous …

Jul 12, 2019 · Originally identified as a B-cell chemoattractant, CXCL13 exerts important functions in lymphoid neogenesis, and has been widely implicated in the pathogenesis of a number of …

Feb 8, 2025 · CXCL13 chemokine is a novel player in multiple myeloma osteolytic microenvironment, M2 macrophage polarization, and tumor progression. CXCL13 is elevated …

Jul 19, 2021 · It is well-established that the chemokine C-X-C motif ligand 13 (CXCL13) and its receptor, the G-protein coupled receptor (GPCR) CXCR5, play fundamental roles in …

May 15, 2022 · These results suggested that CXCL13 has an important role in regulating IL-10-producing B cells in tumor metastasis and might be a promising target for improving …

CXCL13/CXCR5-associated immune activities orchestrate highly specific B cell–T cell interactions required for protective high-affinity antibody responses in SLO, their balance being of utmost …

Jul 22, 2020 · Here the authors show, using imaging and computer simulation, that the chemokine CXCL13 originated from follicular reticular cells in the lymph nodes forms both soluble and …

Sep 13, 2021 · By interacting with the CXCR5 receptor, CXCL13 facilitated vascular endothelial growth factor (VEGF) expression and angiogenesis in EPC through the PLC, MEK, and AP-1 …