
Infusion of Cytotoxic T Cells for the Prevention and Treatment of ...
Sep 1, 1998 · Overall, 0 of 39 patients receiving CTL prophylaxis developed EBV lymphoma, compared with an incidence of 11.5% (7/61) in the control group in our own center. It is …
Cytotoxic T lymphocyte therapy with donor T cells prevents and …
Nov 5, 2009 · We now show that infusions of single cytotoxic T lymphocyte (CTL) lines (5 × 10 6 -1.35 × 10 8 cells/m 2) with specificity for 2 commonly detected viruses, Epstein-Barr virus …
Long-term outcome of EBV-specific T-cell infusions to prevent or …
Feb 4, 2010 · To address questions of long-term efficacy, safety, and practicality, we studied 114 patients who had received infusions of EBV-specific cytotoxic T lymphocytes (CTLs) at 3 …
Systemic infusion of TLR3-ligand and IFN-α in patients with breast ...
The ability of toll-like receptor 3 (TLR3) ligands, interferons (IFNs) and COX2 inhibitors to synergistically induce CTL-attracting chemokines (but not regulatory T cell (Treg)-attractants) …
Systemic infusion of TLR3-ligand and IFN-α in patients with breast ...
Intratumoral CD8 + T cell (cytotoxic T lymphocytes (CTL)) infiltration predicts clinical outcomes in patients with multiple cancer types, 1–3 including breast, 4–6 and their responsiveness to …
mRNA transfection improves CTL response in immunotherapy
In a 2022 study, Mayo Clinic researchers found that by transfecting cytotoxic CD8+ T cells with mRNA of natural killer cells they can improve response in patients previously not responding …
Clinical safety of induced CTL infusion through recombinant …
Jul 19, 2012 · The aim of the study is to explore the safety of cytotoxic T lymphocytes (CTLs) infusion by transfected dendritic cells (DCs) with recombinant adeno-associated virus vector …
Induction and Measurement of Cytotoxic T Lymphocyte Activity
Feb 21, 2018 · Cytotoxic T cells (CTLs) are important immune effector cells in the adaptive immune response. It has been well documented that CTLs are important in host immune …
Induction of Cytotoxic T-Lymphocyte Responses Upon ... - PubMed
Apr 30, 2018 · There is an unmet medical need for new subunit vaccines that induce cytotoxic T-lymphocyte (CTL) responses to prevent infection with a number of pathogens. However, …
Early cART and cART in Combination With Autologous HIV-1 …
The purpose of this study is to assess the ability of the early initiation of cART or cART in combination with autologous HIV-1 specific cytotoxic T lymphocyte (CTL) infusion to achieve a …
- Some results have been removed