
ILD can be seen in all CTDs but most commonly in rheumatoid arthritis (RA), systemic sclerosis (SSc), and idiopathic inflammatory myopathy (IIM). This primer will focus on the general features of CTD-ILDs along with distinct features noted in RA, SSc, and IIM-associated ILD.
Connective tissue disease-related interstitial lung disease (CTD-ILD ...
Mar 18, 2025 · The baseline lung function, prognosis and treatment of CTD-ILD differs from that of idiopathic ILD, so the distinction is clinically important. CTD-ILD is frequently symmetrical and lower lobe predominant with volume loss.
Connective tissue disease-related interstitial lung disease (CTD-ILD ...
In IPAF subjects, on TSCT or surgical lung biopsy, ILDs of similar patterns are identified as in CTD-ILD. In patients with CTD-ILD and UIP pattern, straight edge sign, exuberant HC sign and anterior upper lobe sign are significantly more common on …
Pulmonary involvement in connective tissue diseases
Nov 16, 2023 · general approach to CTD-ILD with rapidly progressive ILD (RP-ILD) overall concept: a general approach to RP-ILD. RP-ILD (rapidly progressive ILD) may be roughly defined as progressively deteriorating hypoxemia and pulmonary infiltrates within a …
Understanding Interstitial Lung Diseases Associated with …
Connective tissue disease-associated interstitial lung disease (CTD-ILD) is a collection of systemic autoimmune disorders resulting in lung interstitial abnormalities or lung fibrosis. CTD-ILD pathogenesis is not well characterized because of disease heterogeneity and …
Management of Connective Tissue Disease–related Interstitial Lung Disease
This review aims to collate current evidence on the screening, diagnosis, and treatment of various connective tissue disease (CTD)–associated interstitial lung diseases (CTD-ILD) and present a contemporary framework for the management of such patients.
What is CTD-ILD? - UCLA Health
CTD-ILD causes inflammation and scarring (fibrosis) of the lungs. Some patients with ILD may have features of a CTD, but not meet all of the criteria necessary to diagnosis a specific autoimmune disease.
2020 guide for the diagnosis and treatment of interstitial lung disease ...
The prognosis of patients with connective tissue disease (CTD) has improved significantly in recent years, but interstitial lung disease (ILD) associated with connective tissue disease (CTD-ILD) remains a refractory condition, which is a leading cause of mortality.
Connective Tissue Disease-Interstitial Lung Disease-Associated …
Aug 6, 2021 · Connective tissue diseases (CTD) are a diverse group of systemic disorders characterized by autoimmune-mediated organ damage. Interstitial lung disease (ILD) is an extra-articular complication that is seen commonly in many CTDs and, if left untreated, can lead to significant morbidity and death.1,2
Treatment of the Connective Tissue Disease–Related Interstitial …
Interstitial lung disease (ILD) is a frequent complication of patients with connective tissue disease (CTD) and significantly affects morbidity and mortality. Disease course may vary from stable or mildly progressive to more severe, with rapid loss of lung function.