Dec 6, 2014 · Central nervous system (CNS) involvement is considered rare in adults with acute myeloid leukemia (AML). Therefore the cerebrospinal fluid (CSF) is typically examined only in …

AML CNS involvement was defined as unequivocal morphologic or immunophenotypic evidence of leukemic blasts in the CSF, or, in symptomatic patients by abnormal findings on computed …

Involvement of the central nervous system (CNS) by acute myeloid leukemia (AML) is an adverse finding that can lead to potentially devastating complications. CNS involvement can manifest …

After a first study showed that GM-CSF following chemotherapy effectively accelerated neutrophil recovery and reduced early mortality in high risk patients with AML, a second study was begun …

Acute myeloid leukemia (AML) is a rare and aggressive malignancy that can present with a broad range of clinical manifestations. Central nervous system (CNS) involvement is rarely …

Granulocyte colony-stimulating factor (G-CSF) reduces the incidence, duration, and severity of neutropenia [3]. However, its prophylactic use for AML remains controversial due to a …

Jun 24, 2010 · Use of glycosylated recombinant human G-CSF (lenograstim) during and/or after induction chemotherapy in patients 61 years of age and older with acute myeloid leukemia: …

The clinical application of recombinant human G-CSF in patients with acute myeloid leukemia (AML) has been controversial because it stimulates the in vitro proliferation of leukemic cells.

The role of G-CSF in the biology of acute myeloid leukemia (AML) has been investigated by several authors, who have demonstrated receptor mediated enhanced proliferation of AML …

We analyzed the effects of granulocyte colony-stimulating factor (G-CSF) on outcomes in 315 anthracycline-based induction chemotherapy-treated patients with non-M3 acute myelogenous …