It mimics a fully processed mature mRNA. CleanCap ® Reagent AG produces a base-modified Cap-1 mRNA, which shows superior in vivo activity compared to Cap-0 mRNA produced by …

Cre recombinase is a widely used tool in the field of molecular biology. The enzyme's unique and specific recombination system is exploited to manipulate genes and chromosomes in a huge …

Oct 13, 2023 · LNP variants deliver Cre mRNA in Ai9 mice. We subretinally delivered Cre-recombinase mRNA encapsulated LNP variants to test their ability to transfect retina in-vivo.

To more rapidly identify which types of cells an mRNA formulation transfects in vivo, we describe a Cre recombinase (Cre)-based system that permanently expresses fluorescent tdTomato …

RLPs deliver mature mRNA that leads directly to transient protein expression. There is no waiting for promoter-driven translation and there is no genomic integration. These VSV-G …

Jan 29, 2023 · To evaluate functional Cre mRNA transfer through EVs, Ai9 reporter cells were incubated with three different doses of Cre EVs (2.2, 4.4 and 13.1 ×10 9 particles) for 72 hours …

The cre-loxP-mediated recombination system is an integral experimental tool for mammalian genetic and cell biology. This mRNA is capped with Cap1 structure with high capping …

Cre recombinase is a tyrosine recombinase that catalyzes recombination between two loxP sites. The Cre mRNA is capped using m7G(5′)ppp(5′)A analog and polyadenylated to mimic a fully …

TriLink offers RUO and GMP custom CleanCap® Cap-1 mRNA production services in addition to our catalog mRNA offerings. Visit our Visit our website trilinkbiotech.com/mrna-cdmo-services …

Apr 4, 2025 · The Cre-Lox system is a powerful tool in mouse genetics, enabling precise spatiotemporal control of gene expression and conditional knockout models. Since its …