Feb 2, 2024 · These organisms are known as carbapenem-resistant Enterobacterales (CRE). CRE are defined by resistance to at least 1 carbapenem or the presence of a carbapenemase. Mechanisms of carbapenem resistance include carbapenemase production, efflux pumps, or decreased porin expression.

Cre recombinase is a widely used tool in the field of molecular biology. The enzyme's unique and specific recombination system is exploited to manipulate genes and chromosomes in a huge range of research, such as gene knock out or knock in studies.

Nov 13, 2023 · Carbapenem-resistant Enterobacterales (CREs) are certain kinds of bacteria that carbapenems (commonly used antibiotics) aren’t effective against. They can cause bloodstream infections, UTIs, pneumonia and other infections. These can be life-threatening and are hard to treat. What are carbapenem-resistant Enterobacterales (CREs)?

Apr 11, 2024 · Carbapenem-resistant Enterobacterales (CRE) are germs resistant to one or several antibiotics called carbapenems. In 2017, CRE caused about 13,100 infections in hospital patients and about 1,100 deaths in the United States. 1

The global spread of carbapenem-resistant Enterobacteriaceae (CRE) has been fostered by the lack of preemptive screening of patients in healthcare facilities that could prevent patient-to-patient transmission. Outbreaks of CRE infections have led ...

Cre-Lox recombination is a special type of site-specific recombination developed by Dr. Brian Sauer and patented by DuPont that operated in both mitotic and non-mitotic cells, and was initially used in activating gene expression in mammalian cell lines.

The Cre-lox system is one of the most revolutionary tools in the geneticist's toolbox. You don't have to be a user or developer of cre or floxed mice to appreciate the impact that cre-lox technology has had on biomedical research and genetic engineering.

Carbapenem-resistant Enterobacteriaceae (CRE) or carbapenemase-producing Enterobacteriaceae (CPE) are gram-negative bacteria that are resistant to the carbapenem class of antibiotics, considered the drugs of last resort for such infections.

Cre (Cre recombinase) is one of the tyrosine site-specific recombinases (T-SSRs) including flipase (Flp) and D6 specific recombinase (Dre) [1,2]. it was discovered as a 38-kDa DNA recombinase produced from cre (cyclization recombinase) gene of bacteriophage P1 [3,4,5,6].

Carbapenem-resistant Enterobacteriaceae (CRE) have become a public health threat worldwide. There are three major mechanisms by which Enterobacteriaceae become resistant to carbapenems: enzyme production, efflux pumps and porin mutations.