Collagen alpha-5(IV) chain is a protein that in humans is encoded by the COL4A5 gene. This gene encodes one of the six subunits of type IV collagen, the major structural component of …

Mar 28, 2025 · COL4A5 (Collagen Type IV Alpha 5 Chain) is a Protein Coding gene. Diseases associated with COL4A5 include Alport Syndrome 1, X-Linked and X-Linked Alport Syndrome …

Alport syndrome (AS) is an inherited progressive nephropathy caused by mutations in one or two of the type IV collagen novel chains (α3, α4 and α5), which are encoded by COL4A3, COL4A4 …

The COL4A5 gene provides instructions for making one piece of a protein called collagen IV. Specifically, this gene makes the alpha5 (IV) chain of collagen IV. This chain combines with …

COL4A5 encodes an alpha chain of type IV collagen, the major component of basement membranes (Hostikka et al., 1990). Hostikka et al. (1990) identified a distinct type IV collagen …

We identified 11 pathogenic variants in the type IV collagen genes (COL4A3, COL4A4 and COL4A5). These pathogenic variants include eight missense mutations, two nonsense …

Dec 10, 2024 · Clinical resource with information about COL4A5, Alport syndrome, X-linked Alport syndrome, and available tests. There are links to practice guidelines and authoritative …

Feb 8, 2025 · Title: Genetic and molecular dynamics analysis of two variants of the COL4A5 gene causing Alport syndrome. Type IV collagen alpha5 chain promotes luminal breast cancer …

We found high mRNA expression of COL4A5 was correlated with poor OS. Multivariate analysis indicated that age, gender, pathological grade, metastasis, and COL4A5 expression are …

The COL4A5 gene provides instructions for making one piece of a protein called collagen IV. Specifically, this gene makes the alpha5(IV) chain of collagen IV. This chain combines with …