Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40k Da in size that in humans is encoded by the CHI3L1 gene. [5][6][7] The …

Mar 30, 2025 · CHI3L1 (Chitinase 3 Like 1) is a Protein Coding gene. Diseases associated with CHI3L1 include Asthma-Related Traits 7 and Schizophrenia. Among its related pathways are …

Jan 4, 2024 · Chitinase-3-like protein 1 (CHI3L1) is a secreted glycoprotein that mediates inflammation, macrophage polarization, apoptosis, and carcinogenesis. The expression of …

Sep 14, 2020 · Non-enzymatic chitinase-3 like-protein-1 (CHI3L1) belongs to glycoside hydrolase family 18. It binds to chitin, heparin, and hyaluronic acid, and is regulated by extracellular matrix...

Chitinase-3-like protein 1 (CHI3L1) is a secreted glycoprotein that mediates inflammation, macrophage polarization, apoptosis, and carcinogenesis. The expression of CHI3L1 is …

Chitinase-3-like protein 1 (CHI3L1), a chitinase-like protein family member, is a secreted glycoprotein that mediates macrophage polarization, inflammation, apoptosis, angiogenesis, …

Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis. Chitinase 3-like-1 and fibronectin in the cargo of …

Sep 14, 2020 · Non-enzymatic chitinase-3 like-protein-1 (CHI3L1) belongs to glycoside hydrolase family 18. It binds to chitin, heparin, and hyaluronic acid, and is regulated by extracellular …

Feb 10, 2025 · Yu et al. demonstrate that CHI3L1 is essential for inducing proneural-mesenchymal transition (PMT) through the STAT3-CCD domain of tumor cells and macrophages.

Jan 18, 2025 · Chitinase-3-like-1 (CHI3L1) is an evolutionarily conserved protein involved in key biological processes, including tissue remodeling, angiogenesis, and neuroinflammation. It has …