Nov 13, 2019 · We recently reported that dopamine D1 receptor in the medial prefrontal cortex (mPFC) is activated by subthreshold social defeat stress and suppresses the induction of depressive-like behavior in...

Oct 30, 2024 · Our study evidenced the concurrent activation of glial cells in the medial prefrontal cortex (mPFC), which exhibited minimal c-Fos expression under control conditions but presented a significant 20–30 % increase in response to acute stress.

Oct 12, 2024 · The medial prefrontal cortex (mPFC), particularly in acute stress conditions, undergoes significant physiological changes to cope with the demands associated with cellular activation.

Jan 15, 2019 · Impaired function in the medial prefrontal cortex (mPFC) contributes to depression, and the therapeutic response produced by novel rapid-acting antidepressants such as ketamine are...

Dec 24, 2019 · Using cFos as a marker of neuronal activity, we confirmed that the previously reported chronic stress-induced increase in total PV mRNA in the PFC 7 corresponds to increased activity of PV +...

Dec 11, 2023 · In this study, we found that mPFC neurons projecting to the nucleus accumbens (mPFC-NAc) encode social winning behavior, whereas mPFC neurons projecting to the ventral tegmental area (mPFC-VTA) encode social losing behavior.

Previous studies using glutamate receptor antagonists have revealed that the medial prefrontal cortex (mPFC) plays a central role in associative recognition memory. The present study investigates short-term recognition memory using optogenetics to target glutamatergic neurons within the rodent mPFC specifically.

Nov 13, 2019 · We recently reported that dopamine D1 receptor in the medial prefrontal cortex (mPFC) is activated by subthreshold social defeat stress and suppresses the induction of depressive-like behavior in mice.

Nov 21, 2018 · The present study set out to assess the possible role of the medial prefrontal cortex (mPFC) cannabinoid CB1 receptors and BDNF/cFOS signaling pathways in morphine–dextromethorphan (DXM) cross state-dependent memory (SDM) …

Feb 9, 2023 · Several lines of evidence suggest that neural activity in the medial prefrontal cortex (mPFC) is important for social behavior and subregions of the mPFC are differentially activated following social interaction.