Defining features of hereditary lobular breast cancer due to CDH1 …
Sep 27, 2023 · Women with germline pathogenic variants in CDH1, which encodes E-cadherin protein, are at increased lifetime risk of invasive lobular carcinoma (ILC). The associated …
Hereditary Gastric and Breast Cancer Syndromes Related to CDH1 …
The ongoing trial “Understanding how CDH1 germline mutations affect HLBC” is a clinical genetic study that aims to identify the role of CDH1 in HLBC without DGC aggregation. The first aim of …
Association Between Hereditary Lobular Breast Cancer Due to CDH1 ...
To assess gastric cancer risk among patients who received a diagnosis of hereditary lobular breast cancer (HLBC) owing to a germline loss-of-function variant in CDH1 by establishing …
Women with germline pathogenic variants in CDH1, which encodes E-cadherin protein, are at increased lifetime risk of invasive lobular carcinoma (ILC). The associated tumor …
CDH1 germline mutations in families with hereditary lobular breast ...
May 1, 2022 · Pathogenic CDH1 germline mutations are associated with lobular breast cancer in the so-called hereditary lobular breast cancer (HLBC) syndrome, without apparent correlation …
Defining features of hereditary lobular breast cancer due to CDH1 …
Sep 27, 2023 · Women with germline pathogenic variants in CDH1, which encodes E-cadherin protein, are at increased lifetime risk of invasive lobular carcinoma (ILC). The associated …
Hereditary Gastric and Breast Cancer Syndromes Related to CDH1 …
Jun 17, 2020 · The identification of CDH1 germline mutations in cases of LBC not associated with the classical HDGC syndrome has led to the formation of a working group aimed at better …
CDH1 Linked With New Hereditary Breast Cancer Syndrome
Jun 8, 2024 · Pathogenic variants of CDH1 identify a form of hereditary lobular BC (HLBC) that is unrelated to the better-known breast-ovarian syndrome linked to alterations in BRCA1 and …
Defining features of hereditary lobular breast cancer due to CDH1 …
Women with germline pathogenic variants in CDH1, which encodes E-cadherin protein, are at increased lifetime risk of invasive lobular carcinoma (ILC). The associated tumor …
Hereditary Lobular Breast Cancer: A Newly Defined Syndrome
Mar 17, 2023 · The 2020 consensus guidelines on the diagnosis and management of hereditary diffuse gastric cancer (HDGC) defined HLBC, and incorporated it into a comprehensive …