CD8 + T cells are an important component of the adaptive immune system involved in infection control and cancer immunosurveillance. They express the T cell receptor (TCR) and the CD8 …

CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Along with the TCR, the CD8 co-receptor plays a role in T cell …

CD8 + T cells are pivotal for the recognition and clearance of cells infected by intracellular pathogens 1 and are the key players in antitumor immune response. 2 They receive activation …

Using a combination of Thymic Leukemia (TL) antigen tetramer, which directly binds CD8αα, anti-CD161, and anti-Vα7.2 antibodies we have been able for the first time to clearly define CD8αα …

Mar 20, 2025 · CD8 T cells play a crucial role in immune defense by identifying and eliminating infected or malignant cells. Their activation status is determined by specific surface markers …

Apr 1, 1999 · In response to viral infections, the immune system mounts an effective cytotoxic T lymphocyte (CTL) response, primarily executed by CD8 + T cells, which recognize viral …

Apr 8, 2025 · Bulk CD8 + T cells within both healthy controls (HC) and patients with COVID-19 were clustered into distinct nodes based on similarity in phenotypic markers, and the …

Nov 28, 2023 · Dual-specific CD8 + T cells potently kill MHC class II-expressing tumor cells. Major histocompatibility complex (MHC) class II-reactive CD8 + T cells are found in humans and …

Aug 28, 2022 · Background: The adaptive antiviral immune response requires interaction between CD8+ T cells, dendritic cells, and Th1 cells for controlling SARS-CoV-2 infection, but the data …

We found that the CD107a and TNF-α produced by CD11c + CD8 + T cells in HCC group were significantly decreased compared with that in HC group, while IL-2 and IFN-γ levels between …