Expression of CD68 (DKFZp686M18236, GP110, LAMP4, SCARD1) in spleen tissue. Antibody staining with HPA048982, CAB000051, CAB000066, CAB072861 and CAB072862 in immunohistochemistry.

The interruption of this CD68 + linear pattern in splenic marginal zone lymphoma cases could be a criterion to differentiate it from reactive hyperplasia. CD45RO, CD20, CD21, CD68 and SMA-1 provide a basic and quality immunohistochemical battery for a better comprehension of the human spleen and could improve its histopathological diagnosis.

May 20, 2008 · We highlight the substantial heterogeneity of cells in both normal liver and spleen that stain for F4/80, CD68, CD11b, and CD11c. Using diet-induced steatohepatitis as a model of liver inflammation, we show that CD11b is expressed by newly migrating macrophage precursors, but is an unreliable marker for macrophage precursors when used alone ...

Tissue-resident macrophages in the spleen, including red pulp and white pulp macrophages, marginal zone macrophages (MZMs) and marginal zone metallophilic macrophages (MMMs), are highly heterogeneous as a consequence of adaptation to tissue-specific environments.

Jun 12, 2024 · C57BL/6N mice were restrained for different durations (1, 3, 7, 14 and 21 days) for 6–8 h daily. The control mice were observed at the same time points. Post restraint, behavioural...

This application protocol describes the flow cytometric analysis of macrophages after spleen dissociation from healthy C57BL/6 mice. Mouse spleens are easily dissociated using the gentleMACS™ Dissociators to quickly obtain viable single cell suspensions ready for flow cytometric analysis.

The tangible body macrophages within the splenic white pulp can be distinguished from other macrophages by expression of CD68 (CD11b − F4/80 − CD68 +) (Table1), and their involvement in the phagocytosis of apoptotic B cells generated during germinal centre reactions.

CD68 is a valuable marker which can be used to identify macrophages and monocytes, and also has implications in the diagnosis of various disease conditions. Bio-Techne offers various CD68 reagents for your research needs including: Written by Emma Easthope.

Mouse-over function shows protein score for analyzed cell types in a selected tissue. To access image data click on tissue name or bar. Annotation of protein expression is described in detail in Assays & annotation.