Who is hematopoietic stem cell: CD34+ or CD34-? - PubMed
CD34 is a marker of human HSC, and all colony-forming activity of human bone marrow (BM) cells is found in the CD34+ fraction. Clinical transplantation studies that used enriched CD34+ …
Human CD34 - American Society of Hematology
Aug 10, 2023 · In this article, we will critically review the progress in the delineation of the human postnatal CD34 + HSC–enriched population by examining the methodologies and approaches …
Concise Review: Evidence for CD34 as a Common Marker for …
CD34 is predominantly regarded as a marker of hematopoietic stem cells (HSC) and hematopoietic progenitor cells. However, CD34 is now also established as a marker of several …
CD34 expression on long-term repopulating hematopoietic stem cells ...
Jan 15, 2001 · Using a competitive long-term reconstitution assay, the results of this study confirm developmental changes in CD34 expression on murine HSC. In fetuses and neonates, CD34 …
CD34—Structure, Functions and Relationship with Cancer Stem Cells
CD34 is primarily known as a biomarker for hematopoietic stem cells (HSCs) and hematopoietic stem precursor cells, but it has also been identified as a marker for several non-hematopoietic …
Not just a marker: CD34 on human hematopoietic stem/progenitor cells ...
Dec 26, 2017 · CD34 is routinely used to identify and isolate human hematopoietic stem/progenitor cells (HSPCs) for use clinically in bone marrow transplantation, but its function …
Human CD34-negative hematopoietic stem cells: The current
Clonal analyses of highly purified human CD34 - HSCs have revealed their potent megakaryocyte/erythrocyte differentiation potential. Based on these observations, we propose …
Single cell analyses identify a highly regenerative and ... - Nature
Apr 19, 2022 · Using various platforms including single cell RNA-sequencing and extensive xenotransplantation, we have uncovered an uncharacterized human CD34 + HSC population.
CD34+ HSC人类免疫系统重建好帮手 - 知乎 - 知乎专栏
CD34+ HSC 免疫重建能在一定程度上克服PBL-HIS模型的缺点，该方法能够实现功能性多系造血细胞的长期移植。 HSC的来源包括成人外周血、脐带血、骨髓或胎儿肝脏。 当HSC注射到成 …
Purification of Human CD34 - Cell Press
Sep 11, 2020 · Current CD34-mediated hematopoietic stem cell (HSC) gene therapy approaches are untargeted and expensive. Purification and targeting of the HSC-enriched CD34+CD90+ …