In this report, we identify the phenotype of distinct subpopulations of myeloid, erythroid and lymphoid cells in liquid suspension culture using differential expression of CD34 vs. CD71 in combination with specific lineage markers.

The results showed that the count of CD34 (+) in MDS group was higher than that in AA (NSAA and SAA) group (P < 0.05). The count of CD71 (+)CD45 (-) cells in MDS group was higher than that in SAA (P < 0.05), there was no significant difference between NSAA group and MDS group.

By combining established surface markers (CD34 and CD36) with CD117 (c-kit), CD71 and CD105, we were able to isolate four distinct erythroid progenitor populations and resolve the continuum of early erythropoiesis.

CD34 is a molecular marker of undifferentiated HSPCs; its absence suggests that the cells have progressed down one of the various hematopoietic cell lineages. 1 Additionally, as they differentiate, the cells express various markers that are commonly used to indicate lineage: GlyA and CD71 for erythroid (red blood cell precursor) progenitor ...

Jun 15, 2007 · Localization of CD53, CD62L, CD63, and CD71 in polarized CD34 + CD133 + cells. CD53, CD63, and CD71 are localized in vesicular-like structures at the base of the uropod. In addition, CD71 is expressed all over the cell surface, including the leading edge (left side of the cell shown in column 2).

CD71 + 41 + CD42+ cells showed significantly lower expression of erythroid genes (e.g. ANK1, CD71, MYB), genes associated with more primitive HSC/progenitors (e.g. CD34, CD44) and higher expression of megakaryocyte genes (e.g. VWF, CD61, CLU, NF1B) than CD71 + …

CD34 has been suggested to play a fundamental role in the regulation of muscle progenitor cell differentiation and establishment and maintenance of a satellite cell population 71. CD34 is not expressed on all muscle satellite cells but is used in identification alongside other markers including CD56 16, 17.

This study will examine the differentiation and expansion potential of bone marrow-derived (BM) CD34+ cells into erythroid cells, mega- karyocytes, and myeloid precursor cells in a liquid, non-adherent culture format.

Nov 11, 2021 · CD71 increases and co-expresses with CD34 at the early stages of erythropoiesis and is highly expressed in CFU-E and proerythroblasts (ProE). CD71 is gradually downregulated from the late...

Sep 22, 2015 · We chose CD34, CD71 and CD235a markers to study erythroid EVs. We characterised the EVs immunophentoypic profiles of 13 DBA patients, 22 healthy controls and 16 patients with other haematological diseases.