Alternatively, CD44 might play a direct co-stimulatory role in T cell activation, as suggested by studies using cross-linking anti-CD44 antibodies in vitro. Finally, CD44 could promote T cell …

CD44 is a prominent activation marker which distinguishes memory and effector T cells from their naïve counterparts. It also plays a role in early T cell signaling events as it is bound to the …

To define the activation status of splenic and circulating CD4 + T and CD8 + T cells, we use anti-CD44 and anti-CD62L antibodies, resulting in plots with CD44 − CD62L + naive, CD44 + …

小鼠先天免疫系统的自然杀伤 (nk) 细胞可通过激活性和抑制性受体的组合来检测并杀死癌细胞，其中该组合可让自然杀伤细胞杀死癌细胞而不会损伤宿主。可以通过 nkg2d、nk1.1 或 nkp46 的 …

CD3 + CD4-CD8-double-negative (DN) T cells, although constituting a rare subset of peripheral T cells, are gaining interest for their roles in inflammation, immune disease and cancer. Herein, …

Cross-linking of CD44 induces proliferation of peripheral T cells and apoptosis of thymocytes and a T helper line in the presence of subthreshold levels of anti-CD3. Several proteins are rapidly …

Jan 17, 2006 · CD44 is a glycoprotein that is expressed on the surface of numerous cell types, including leukocytes, fibroblasts, epithelial cells and endothelial cells [1]. It is a major receptor …

4 days ago · Naïve, memory, and effector T cells in mice can be distinguished through expression of CD62L, IL7Ra, and CD44. Multiple cytokine-producing subsets of CD4 + cells are …

Despite the widespread use of the cell-surface receptor CD44 as a marker for antigen (Ag)-experienced, effector and memory T cells, surprisingly little is known regarding its function on …

CD44 expression is an indicative marker for effector-memory T-cells. Memory cell proliferation (activation) can also be assayed in vitro with CFSE chemical tagging. In addition, variations in …