CD274 KO cell line available to order. KO validated by Western blot. Free of charge wild type control provided. Knockout achieved by using CRISPR/Cas9, 1 bp insertion in exon 4 and 2 bp deletion in exon 4 and 7 bp deletion in exon 4.

Mar 10, 2025 · The efficacy of DMXAA was not further enhanced in Cd274-KO mice inoculated with sgCd274 cells compared to those inoculated with sgNC cells (Figures S1C–S1E). These findings suggest that the critical role of host PD-L1 in constraining the …

What Does This Nomenclature Mean? Immunized CD274 (PD-L1) knockout mice develop severe EAE. Mice exhibit resistance to Leishmania mexicana and a decrease in IL4 producing cells (suggesting an impaired Th2 response) and increased …

The CD274 Knockout cell line (A549) is constructed based on (1) the optimal design of the Red Cotton System, (2) CRISPR-U™ technology with efficiency 10-20 times higher than traditional methods, and (3) our exclusive EZ-editor™ product series. This cell line is …

Human CD274 KO cell line was engineered from HAP1 by CRISPR/Cas9 technology to contain a frameshift mutation in a coding exon. Glow Biologics can also help you to make the ko cell lines from other host cell lines.

Ubigene 786-O CD274 KO: Synonyms: CD274 Knockout cell line (786-O) Accession: CVCL_D7IW: Resource Identification Initiative: To cite this cell line use: Ubigene 786-O CD274 KO (RRID:CVCL_D7IW) Comments: Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:17635; CD274.

Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes. Belongs to the immunoglobulin superfamily. BTN/MOG family.

Sep 10, 2024 · Derived from site: In situ; Colon; UBERON= UBERON_0001155. Breed/subspecies: C57BL/6.

CD274 KO cell line available to order. KO validated by Western blot. Free of charge wild type control provided. Knockout achieved by using CRISPR/Cas9, Homozygous: 1 bp insertion in exon 4.

Mar 30, 2025 · CD274 (CD274 Molecule) is a Protein Coding gene. Diseases associated with CD274 include Hematologic Cancer and Leukemia, Acute Lymphoblastic. Among its related pathways are Signaling by ALK and Phosphorylation of CD3 and TCR zeta chains. An important paralog of this gene is PDCD1LG2.