May 21, 2024 · Immunohistochemically, the infiltrate is positive for CD20, CD5, CD23 and BCL2. The staining for CD3 shows numerous accompanying reactive T lymphocytes. The stains for cyclin D1, BCL6 and CD10 remain negative in the lymphocytic infiltrate but BCL6 and CD10 are positive in a few residual reactive germinal centers.

Immunostains, routine stains and CD markers at PathologyOutlines.com

CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels.

5 days ago · Follicular dendritic cells form a reticular network in the lymphoid follicle necessary to retain and present native antigens (in the form of antigen antibody immune complexes) to B cells during the secondary immune response CD21, CD23 and CD35 are dendritic cell markers Clinical features: Reduced expression in erythrocytes in:

Identification of follicular dendritic cells. Classification of low-grade B-cell lymphomas. For the initial technical component only immunohistochemical (IHC) stain performed, the appropriate bill-only test ID will be reflexed and charged (IHTOI).

Clinical Information CD23 (cluster of differentiation 23) strongly stains the cytoplasm and membranes of follicular dendritic cells and the membranes of a subset of follicular mant.

CD23 (cluster of differentiation 23) strongly stains the cytoplasm and membranes of follicular dendritic cells and the membranes of a subset of follicular mantle zone B-lymphocytes.

Jan 22, 2025 · CD23 is most useful in distinguishing B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) from other entities and may remain present in CLL/SLL that has undergone large cell transformation.

Strong membranous staining in the follicular dendritic cells and at least weak to moderate staining in the activated B-cells of the mantle zones. Appendix / tonsil is recommended tissue control for CD23. The follicular dendritic cells of the germinal centers must …

Dec 6, 2014 · The CD23 protein can be cleaved and released into the serum as a soluble form of CD23 (sCD23). The sCD23 is a 25kDa fragment that can be found in serum, plasma and urine in patients with chronic lymphocytic leukemia.