MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old woman. [1] MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. [2]

Feb 15, 2008 · Monoclonal antibody FMC7 detects a conformational epitope on the CD20 molecule: evidence from phenotyping after rituxan therapy and transfectant cell analyses.

When grown in 3D using scaffold-free agarose hydrogels, MCF-7 human breast cancer cells self-organize to form directionally-oriented microtissues that contain a luminal space, reminiscent of the in vivo structure of the mammary gland.

In this work, we quantitatively analyze time-course microarray data of MCF-7 cells, and identify the key genes, i.e., dynamical network biomarker (DNB), which may indicate the imminent critical transition of the cancer cells during cell differentiation or proliferation.

No measurable amounts of matrix metalloproteinases (MMPs) were produced by human breast adenocarcinoma cell lines MCF-7 and BT-20 in culture. When MCF-7 cells were co-cultured with human dermal fibroblasts enhanced production of precursors of MMP-1 ...

Chromosome 20 was nullisomic and X was disomic. The MCF7 line retains several characteristics of differentiated mammary epithelium including ability to process estradiol via cytoplasmic estrogen receptors and the capability of forming domes. The cells express the WNT7B oncogene.

May 1, 1995 · No measurable amounts of matrix metalloproteinases (MMPs) were produced by human breast adenocarcinoma cell lines MCF-7 and BT-20 in culture.

The current paper provides a broad description of the MCF-7 cell line, including the molecular profile, proliferation, migration, invasion, spheroid formation, its involvement in angiogenesis and lymphangiogenesis and its interaction with the mesenchymal stem cells.

Aug 1, 2021 · After incubation of the MCF-7 breast cancer cell line with ABL-CaCO 3 NPs and DOX for 24 h, a 2-DE based proteomics technique was used to detect changes in protein abundance.

Dec 1, 2024 · This study pioneers the utilization of native collagen as probes for effectively recognizing MCF-7 cells, and scrutinizes the performance disparities among collagens from diverse sources in MCF-7 cell recognition.